ArtNr |
BOS-A04233 |
Hersteller |
Boster
|
Menge |
100ul |
Kategorie |
|
Typ |
Antibody |
Format |
Liquid |
Applikationen |
WB, IF, IHC |
Specific against |
Human |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Complement C1q subcomponent subunit B;C1QB; |
Lieferbar |
|
Manufacturers Product Category |
Primary Antibodies |
Manufacturers Research Category |
Alzheimer's Disease, Complement, Immunology, Innate Immunity, Neurodegenerative Disease, Neurology Process, Neuroscience |
Short Description |
Boster Bio Anti-C1QB Antibody (Catalog # A04233). Tested in WB, IHC, IF applications. This antibody reacts with Human. |
Description |
Boster Bio Anti-C1QB Antibody (Catalog # A04233). Tested in WB, IHC, IF applications. This antibody reacts with Human. |
Background |
C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca2+-dependent C1r2C1s2 proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.
Reid K.B.M.; Biochem. J. 231:729-735(1985). Gregory S.G., Nature 441:315-321(2006). The MGC Project Team; Genome Res. 14:2121-2127(2004). |
Gene Name |
C1QB |
Clonality |
Polyclonal |
Concentration |
1 mg/ml |
Contents |
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Application Details |
Western blotting: 1:500~1:3000
Immunofluorescence: 1:100~1:500 |
Immunogen |
Synthesized peptide derived from internal of human C1QB. |
Purification |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Storage |
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Gene Full Name |
Complement C1q subcomponent subunit B |
Molecular Weight |
26722 MW |
Protein Function |
C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca (2+)-dependent C1r (2)C1s (2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes. |
Subcellular Localization |
Secreted. |
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