ArtNr |
BOS-PB9566 |
Hersteller |
Boster
|
Menge |
100 ug/vial |
Kategorie |
|
Typ |
Antibody Polyclonal |
Format |
Lyophilized |
Applikationen |
WB, IHC, ELISA |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
Citations |
1. "Entrez Gene: DKK3 dickkopf homolog 3 (Xenopus laevis)". <br/><br/>2. Krupnik VE, Sharp JD, Jiang C, Robison K, Chickering TW, Amaravadi L, Brown DE, Guyot D, Mays G, Leiby K, Chang B, Duong T, Goodearl AD, Gearing DP, Sokol SY, McCarthy SA (Dec 1999). "Functional and structural diversity of the human Dickkopf gene family". Gene 238 (2): 301–13. <br/><br/>3. Roman-Gomez J, Jimenez-Velasco A, Agirre X et al. (2004). "Transcriptional silencing of the Dickkopfs-3 (Dkk-3) gene by CpG hypermethylation in acute lymphoblastic leukaemia". Br. J. Cancer 91 (4): 707–13. <br/><br/> |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Dickkopf 3 antibody, Dickkopf 3 homolog (Xenopus laevis) antibody, Dickkopf 3 homolog antibody, Dickkopf homolog 3 antibody, Dickkopf related protein 3 antibody, Dickkopf related protein 3 Precursor antibody, Dickkopf WNT signaling pathway inhibitor 3 antibody, Dickkopf, Xenopus, homolog of, 3 antibody, Dickkopf-3 antibody, Dickkopf-related protein 3 antibody, Dickkopf3 antibody, DKK 3 antibody, Dkk-3 antibody, DKK3 antibody, DKK3_HUMAN antibody, hDkk 3 antibody, hDkk-3 antibody, hDkk3 antibody, Regulated in glioma antibody, REIC antibody, RIG antibody, RIG-like 5-6 antibody, RIG-like 7-1 antibody |
Lieferbar |
|
Specificity |
No cross reactivity with other proteins. |
Background |
Dickkopf-related protein 3 is a protein that in humans is encoded by the DKK3 gene. This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein. |
Contents |
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3. |
Description short |
Rabbit IgG polyclonal antibody for Dickkopf-related protein 3(DKK3) detection. Tested with WB, IHC-P, ELISA in Human; Mouse; Rat. |
ELISA |
Concentration: 0.1-0.5ug/ml; Tested Species: Human |
Gene Full Name |
dickkopf WNT signaling pathway inhibitor 3 |
Gene Name |
DKK3 |
Immunogen |
E. coli-derived human Dkk3 recombinant protein (Position: A22-D152). Human Dkk3 shares 85.5% amino acid (aa) sequence identity with mouse Dkk3. |
Immunohistochemistry (Paraffin-embedded Section) |
Concentration: 0.5-1ug/ml; Tested Species: Human, Mouse, Rat |
Notes |
Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users. |
Protein Name |
Dickkopf-related protein 3 |
Purification |
Immunogen affinity purified. |
Reconstitution |
Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
Relevant detection systems |
Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P). |
Storage |
At -20C for one year. After reconstitution, at 4C for one month. It can also be aliquotted and stored frozen at -20C for a longer time. Avoid repeated freezing and thawing. |
Western blot |
Concentration: 0.1-0.5ug/ml; Tested Species: Human, Mouse, Rat |
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