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Anti-CD3 epsilon/CD3E Antibody Picoband™

Anti-CD3 epsilon/CD3E Antibody Picoband™

ArtNr	BOS-PB9093
Hersteller	Boster
Menge	100 ug/vial
Kategorie	Oncology Antibodies By Cell Type Hematology Leukemia Lymphoma Immunohistochemistry Western Blot Immunocytochemistry Primary Antibodies
Typ	Antibody Polyclonal
Format	Lyophilized
Applikationen	WB, IF, IHC, ICC, IHC-F
Specific against	Human, Mouse, Rat, Chicken
Host	Rabbit
Isotype	IgG
Citations	1. Clevers HC, Dunlap S, Wileman TE, Terhorst C (November 1988)."Human CD3-epsilon gene contains three miniexons and is transcribed from a non-TATA promoter". Proc. Natl. Acad. Sci. U.S.A. 85(21): 8156–60. <br/>2. "Entrez Gene: CD3E CD3e molecule, epsilon (CD3-TCR complex)"<br/>3. Gold DP, Puck JM, Pettey CL, Cho M, Coligan J, Woody JN, Terhorst C (1986). "Isolation of cDNA clones encoding the 20K non-glycosylated polypeptide chain of the human T-cell receptor/T3 complex". Nature 321 (6068): 431–4.<br/>
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	T-cell surface glycoprotein CD3 epsilon chain;T-cell surface antigen T3/Leu-4 epsilon chain;CD3e;CD3E;T3E;
Similar products	CD3E antigen, CD3 epsilon antibody, CD3E antibody, CD3E antigen epsilon polypeptide antibody, CD3e molecule epsilon antibody, CD3e molecule, IMD18 antibody, T cell antigen receptor complex epsilon subunit of T3 antibody, T cell surface antigen T3/Leu 4 epsilon chain antibody, T-cell surface antigen T3/Leu-4 epsilon chain antibody, T-cell surface glycoprotein CD3 epsilon chain antibody, T3E antibody, TCRE antibody, CD3e antibody, CD3e antigen epsilon polypeptide (TiT3 complex) antibody, epsilon subunit antibody, epsilon (CD3 TCR complex) antibody, epsilon (CD3-TCR complex) antibody, CD3E_HUMAN antibody, T cell surface glycoprotein CD3 epsilon chain antibody
Lieferbar
Specificity	No cross reactivity with other proteins.
Manufacturers Product Category	Primary Antibodies, Rabbit Polyclonal Antibodies
Manufacturers Research Category	Adaptive Immunity, Hematopoietic Progenitors, Immunology, Stem Cells, T Cells
Short Description	Boster Bio Anti-CD3 epsilon/CD3E Antibody Picoband™ catalog # PB9093. Tested in IF, IHC, IHC-F, ICC, WB applications. This antibody reacts with Chicken, Human, Mouse, Rat.
Description	Boster Bio Anti-CD3 epsilon/CD3E Antibody Picoband™ catalog # PB9093. Tested in IF, IHC, IHC-F, ICC, WB applications. This antibody reacts with Chicken, Human, Mouse, Rat.
Background	CD3e molecule, epsilon also known as CD3E is a polypeptide which in humans is encoded by the CD3E gene which resides on chromosome 11. It is mapped to 11q23.3. The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development.
Gene Name	CD3E
Application Details	Western blot, 0.1-0.5μg/ml, Human Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Mouse, Rat, Chicken, By Heat Immunohistochemistry (Frozen Section), 0.5-1μg/ml, Mouse, Rat Immunocytochemistry , 0.5-1μg/ml, Human Immunofluorescence, 2μg/ml, Human, Mouse, Rat
Application Notes	WB: The detection limit for CD3 epsilon is approximately 0.25ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
Clonality	Polyclonal
Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Contents	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Immunogen	E.coli-derived human CD3 epsilon recombinant protein (Position: D23-I207). Human CD3 epsilon shares 65% amino acid (aa) sequence identity with mouse CD3 epsilon.
Purification	Immunogen affinity purified.
Cross-reactivity	No cross-reactivity with other proteins
Storage	Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Gene Full Name	T-cell surface glycoprotein CD3 epsilon chain
Molecular Weight	23147 MW
Protein Function	The CD3 complex mediates signal transduction.
Subcellular Localization	Membrane; Single-pass type I membrane protein.
Protein Name	T-cell surface glycoprotein CD3 epsilon chain
Sequence Similarities	Contains 1 Ig-like (immunoglobulin-like) domain.

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