Hersteller |
Boster
|
Kategorie |
|
Typ |
Antibody Polyclonal |
Specific against |
Human, Mouse, Rat |
Isotype |
IgG |
Format |
Lyophilized |
Applikationen |
WB |
Menge |
100 ug/vial |
Host |
Rabbit |
ArtNr |
BOS-PA1933 |
Targets |
CCDC6, PSPN |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Lieferbar |
|
Alias |
BRICD6 antibody, BRICHOS domain containing 6 antibody, PSP C antibody, PSPC antibody, PSPC_HUMAN antibody, Pulmonary surfactant apoprotein 2 antibody, pulmonary surfactant apoprotein PSP C antibody, pulmonary surfactant apoprotein-2 SP-C antibody, pulmonary surfactant associated protein C antibody, pulmonary surfactant associated proteolipid SPL pVal antibody, Pulmonary surfactant associated proteolipid SPL(Val) antibody, Pulmonary surfactant protein SP5 antibody, Pulmonary surfactant-associated protein C antibody, Pulmonary surfactant-associated proteolipid SPL(Val) antibody, SFTP 2 antibody, SFTP2 antibody, SFTPC antibody, SFTPC surfactant pulmonary associated protein C antibody, SMDP2 antibody, SP 5 antibody, SP C antibody, SP-C antibody, SP5 antibody, SPC antibody, surfactant associated protein pulmonary 2 antibody, Surfactant protein c antibody, Surfactant proteolipid SPL-pVal antibody, Surfactant pulmonary associated protein C antibody |
Background |
SFTPC(Surfactant pulmonary -associated protein C), also known as SFTP2, SPC, PSP-C or PULMONARY SURFACTANT PROTEIN SP5, is a protein that in humans is encoded by the SFTPC gene. It is a membrane protein which manufactures surfactant. Glasser et al.(1988) assigned the SFTPC gene, symbolized SFTP2 by the Human Gene Mapping nomenclature committee, to chromosome 8 by hybridization to somatic cell hybrid DNA. Wood et al.(1994) identified 4 cosmids at the SFTP2 locus by cDNA hybridization. Using a polymorphic CA repeat in the SFTP2 gene and linkage analysis in 8 CEPH families, they located the gene close to D8S298; maximum lod = 19.3 at theta = 0.01. They regionalized the gene to 8p21 by fluorescence in situ hybridization. Moore et al.(1992) showed that the corresponding mouse gene, Sftp2, maps to chromosome 14. |
Concentration |
Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
Contents |
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. |
Cross reactivity |
No cross reactivity with other proteins |
Description |
Rabbit IgG polyclonal antibody for Pulmonary surfactant-associated protein C(SFTPC) detection. Tested with WB in Human; Mouse; Rat. |
Gene full name |
Pulmonary surfactant-associated protein C |
Gene name |
Sftpc |
Immunogen |
A synthetic peptide corresponding to a sequence at the N-terminus of mouse Prosurfactant Protein C(21-36aa RSQFRIPCCPVHLKRL), identical to the related rat sequence and different from the related human sequence by three amino acids. |
MW |
21055 MW |
Predicted reactivity |
Hamster |
Protein function |
Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air- liquid interface in the peripheral air spaces. |
Protein name |
Pulmonary surfactant-associated protein C |
Purification |
Immunogen affinity purified. |
Recommended detection ystems |
Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot. |
Reconstitution |
Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
Research category |
|cardiovascular|lipids / lipoproteins|lipid metabolism|cholesterol metabolism| signal transduction| cardiovascular|vasculature|vasculature markers|pulmonary| cancer|cancer metabolism|metabolic signaling pathway|metabolism of lipids and lipoproteins| metabolism|pathways and processes|metabolic signaling pathways|lipid and lipoprotein metabolism|types of disease |
Storage |
At -20C for one year. After reconstitution, at 4C for one month. It can also be aliquotted and stored frozen at -20C for a longer time.Avoid repeated freezing and thawing. |
Subcellular localization |
Secreted, extracellular space, surface film. |
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