ArtNr |
BOS-PA1839 |
Hersteller |
Boster
|
Menge |
100 ug/vial |
Kategorie |
|
Typ |
Antibody Polyclonal |
Format |
Lyophilized |
Applikationen |
WB, IHC |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Succinate dehydrogenase cytochrome b560 subunit, mitochondrial;Integral membrane protein CII-3;QPs-1;QPs1;Succinate dehydrogenase complex subunit C;Succinate-ubiquinone oxidoreductase cytochrome B large subunit;CYBL;SDHC;CYB560, SDH3; |
Similar products |
mitochondrial antibody, Succinate dehydrogenase cytochrome b560 subunit, mitochondrial precursor antibody, CYB560 antibody, C560_HUMAN antibody, CYBL antibody, Cytochrome B large subunit of complex II antibody, Integral membrane protein CII-3 antibody, PGL3 antibody, QPs-1 antibody, QPs1 antibody, SDH3 antibody, sdhC antibody, Succinate dehydrogenase complex subunit C antibody, Succinate dehydrogenase complex subunit C integral membrane protein 15kDa antibody, Succinate dehydrogenase cytochrome b560 subunit antibody, Succinate dehydrogenase cytochrome b560 subunit mitochondrial antibody, Succinate-ubiquinone oxidoreductase cytochrome B large subunit antibody |
Lieferbar |
|
Manufacturers Product Category |
Primary Antibodies, Rabbit Polyclonal Antibodies |
Manufacturers Research Category |
Cancer Susceptibility, Cell Biology, Developmental Biology, Energy Metabolism, Energy Transfer Pathways, Epigenetics and Nuclear Signaling, Metabolic Signaling Pathways, Metabolism, Mitochondria, Mitochondrial Metabolism, Organelles, Oxidative Phosphorylation, Oxidative Stress, Pathways and Processes, Signal Transduction, Subcellular Markers, Tags & Cell Markers, Transcription, Tumor Suppressors |
Short Description |
Boster Bio Anti-SDHC Antibody catalog # PA1839. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. |
Description |
Boster Bio Anti-SDHC Antibody catalog # PA1839. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. |
Background |
SDHC (succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa) also known as SDH3, SUCCINATE DEHYDROGENASE CYTOCHROME b. The SDHC gene contains 6 exons. Oostveen et al. (1995) found that in fact it was protein from the bovine SDH3 gene (encoding 1 of the 2 integral membrane proteins) that complemented the hamster mutation. The authors localized the human SDH3 gene to the short arm of chromosome one, within 1 to 2 Mb from the centromere. Additionally, the authors stated that Southern analyses of human genomic DNA suggested that there are multiple SDH3 genes or pseudogenes. Elbehti-Green et al. (1998) confirmed the assignment of the SDHC gene to 1q21 by FISH. Baysal et al. (2004) described a family with PGL3 in which an 8, 372-bp deletion in the SDHC gene was transmitted both maternally and paternally, without evidence of genomic imprinting. |
Gene Name |
SDHC |
Application Details |
Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Rat, Mouse, By Heat Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat |
Application Notes |
Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users. |
Clonality |
Polyclonal |
Concentration |
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml. |
Contents |
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. |
Immunogen |
A synthetic peptide corresponding to a sequence at the N-terminus of human SDHC, different from the related mouse and rat sequences by three amino acids. |
Purification |
Immunogen affinity purified. |
Cross-reactivity |
No cross-reactivity with other proteins |
Storage |
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles. |
Reconstitution |
Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
Gene Full Name |
Succinate dehydrogenase cytochrome b560 subunit, mitochondrial |
Molecular Weight |
18610 MW |
Protein Function |
Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). |
Subcellular Localization |
Mitochondrion inner membrane; Multi-pass membrane protein. |
Protein Name |
Succinate dehydrogenase cytochrome b560 subunit, mitochondrial |
Sequence Similarities |
Belongs to the cytochrome b560 family. |
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