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Anti-EDA Antibody Picoband™

Anti-EDA Antibody Picoband™

ArtNr	BOS-PB9191
Hersteller	Boster
Menge	100 ug/vial
Kategorie	Oncology Antibodies Western Blot Primary Antibodies By Organ Testicular & Prostate Cancer
Typ	Antibody Polyclonal
Format	Lyophilized
Applikationen	WB
Specific against	Human
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Ectodysplasin-A;Ectodermal dysplasia protein;EDA protein;Ectodysplasin-A, membrane form;Ectodysplasin-A, secreted form;EDA;ED1, EDA2;
Similar products	Ectodermal dysplasia 1, Ectodermal dysplasia, Ectodysplasin A, Ectodysplasin A, Ectodysplasin A, anhidrotic antibody, Ectodermal dysplasia protein antibody, Ectodysplasin A antibody, membrane form antibody, secreted form antibody, ECTODYSPLASIN A1 ISOFORM antibody, ECTODYSPLASIN A2 ISOFORM antibody, ECTODYSPLASIN antibody, Ectodysplasin-A antibody, ED1 A1 antibody, ED1 A2 antibody, ED1 antibody, ED1 GENE antibody, Eda A1 antibody, Eda A2 antibody, eda antibody, EDA protein antibody, EDA protein homolog antibody, EDA_HUMAN antibody, EDA1 antibody, EDA1 GENE antibody, EDA2 antibody, HED antibody, ODT1 antibody, Oligodontia 1 antibody, secreted form antibody, STHAGX1 antibody, Ta antibody, Tabby antibody, Tabby protein antibody, X linked anhidroitic ectodermal dysplasia protein antibody
Lieferbar
Manufacturers Product Category	Primary Antibodies, Rabbit Polyclonal Antibodies
Manufacturers Research Category	Developmental Biology, Growth Factors/Hormones, Lineage Markers, Lineage Specification, Signal Transduction, Stem Cells
Short Description	Boster Bio Anti-EDA Antibody Picoband™ catalog # PB9191. Tested in WB applications. This antibody reacts with Human.
Description	Boster Bio Anti-EDA Antibody Picoband™ catalog # PB9191. Tested in WB applications. This antibody reacts with Human.
Background	Ectodysplasin-A is a protein that in humans is encoded by the EDA gene. It is mapped to Xq13.1. The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia.
Gene Name	EDA
Application Details	Western blot, 0.1-0.5μg/ml, Human
Application Notes	WB: The detection limit for EDA is approximately 0.25ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
Clonality	Polyclonal
Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Contents	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Immunogen	E.coli-derived human EDA recombinant protein (Position: A30-S391). Human EDA shares 95% amino acid (aa) sequence identity with mouse EDA.
Purification	Immunogen affinity purified.
Cross-reactivity	No cross-reactivity with other proteins
Storage	Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Gene Full Name	Ectodysplasin-A
Molecular Weight	41294 MW
Protein Function	Seems to be involved in epithelial-mesenchymal signaling during morphogenesis of ectodermal organs. Isoform 1 binds only to the receptor EDAR, while isoform 3 binds exclusively to the receptor XEDAR.
Subcellular Localization	Cell membrane; Single-pass type II membrane protein.
Tissue Specificity	Not abundant; expressed in specific cell types of ectodermal (but not mesodermal) origin of keratinocytes, hair follicles, sweat glands. Also in adult heart, liver, muscle, pancreas, prostate, fetal liver, uterus, small intestine and umbilical chord..
Protein Name	Ectodysplasin-A
Sequence Similarities	Belongs to the tumor necrosis factor family.

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