Anti-GPR120 FFAR4 Antibody

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Polyclonal

FFAR4

The antiserum was produced against synthesized peptide derived from human GPR120. AA range:221-270

Immunogen affinity purified

Receptor for medium and long-chain free fatty acids (FFAs). Signals via a G (q)/G (11)-coupled pathway. Acts as a receptor for omega-3 fatty acids and mediates robust anti- inflammatory effects, particularly in macrophages and fat cells. The anti-inflammatory effects involve inhibition of TAK1 through a beta-arrestin 2 (ARRB2)/TAB1-dependent effect, but independent of the G (q)/G (11)-coupled pathway. Mediates potent insulin sensitizing and antidiabetic effects by repressing macrophage- induced tissue inflammation. May mediate the taste of fatty acids. Mediates FFA-induced inhibition of apoptosis in enteroendocrine cells. May play a role in the regulation of adipocyte development and differentiation.

Boster Bio Anti-GPR120 FFAR4 Antibody catalog # A04709. Tested in ELISA, IF, WB applications. This antibody reacts with Human, Mouse, Rat.

Abundant expression in the intestinal tract. Highly expressed in adipose tissue, small intestine and pancreas.