ArtNr |
BS9162-100 |
Hersteller |
Bioworld Technology, Inc
|
Menge |
100ul |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB, IHC |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
MGC10619, MGC131729, OTTHUMP00000208177, OTTHUMP00000208180, SC6A6, SLC6A6, Sodium- and chloride-dependent taurine transporter, Solute carrier family 6 (neurotransmitter transporter, taurine), member 6, Solute carrier family 6 member 6, TAUT, |
Similar products |
TAUT |
Lieferbar |
|
Swiss-Prot |
P31641 |
Application all |
WB: 1:500ca.1:1000
IHC: 1:50ca.1:200 |
Background |
Taurine is an abundant organic osmolyte that possesses antioxidant and immunomodulatory properties and plays a role in cell volume homeostasis. Taurine is taken up into cells via the taurine transporter (TAUT). TAUT, which is sodium- and chloride-dependent, is a multi-pass membrane protein belonging to the sodium neurotransmitter symporter (SNF) family of proteins. TNFalpha upregulates TAUT expression, while phosphorylation on Serine 322 downregulates it. Overexpression of TAUT protects renal cells from cisplatin-induced nephrotoxicity. |
Product |
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. |
Purification and Purity |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). |
Storage and Stability |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Specificity |
TAUT (G594) pAb detects endogenous levels of TAUT rotein. |
IHC |
Immunohistochemistry (IHC) analyzes of TAUT (G594) pAb in paraffin-embedded human lung carcinoma tissue at 1:100. |
BiowMW |
ca. 70 kDa |
Note |
For research use only, not for use in diagnostic procedure. |
Alternative Name |
MGC10619, MGC131729, OTTHUMP00000208177, OTTHUMP00000208180, SC6A6, SLC6A6, Sodium- and chloride-dependent taurine transporter, Solute carrier family 6 (neurotransmitter transporter, taurine), member 6, Solute carrier family 6 member 6, TAUT, |
Immunogen |
Synthetic peptide, corresponding to amino acids 570-620 of Human TAUT. |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.