TMSB4X polyclonal antibody

P62328

Proteins in the thymosin beta family are highly conserved polar peptides that bind monomeric Actin and thereby inhibit Actin polymerization. These proteins act as the main intracellular G-Actin sequestering peptides. The most abundant thymosin beta family member in mammalian cells and tissues is thymosin beta-4 (Tbeta-4), also designated Seraspenide. Tbeta-4 participates in several cellular events including cancerogenesis, apoptosis, angiogenesis, blood coagulation and would healing. Specifically, Tbeta-4 promotes cell migration and adhesion, accelerates wound healing and reduces inflammation, and becomes upregulated in a wide variety of human carcinomas. Due to the effects of Tbeta-4 in these events, it may become a protein of significant biological and pharmaceutical relevance.

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

TMSB4X pAb detects endogenous levels of TMSB4X protein.

For research use only, not for use in diagnostic procedure.

Recombinant full length Human TMSB4X.