Alias |
LMPX, Macropain epsilon chain, MB1, MGC104214, MGC118075, MGC134464, Multicatalytic endopeptidase complex epsilon chain, Proteasome (prosome, macropain) subunit, beta type, 5, Proteasome beta 5 subunit, Proteasome catalytic subunit 3, Proteasome chain 6, |
Background |
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. |
Alternative Name |
LMPX, Macropain epsilon chain, MB1, MGC104214, MGC118075, MGC134464, Multicatalytic endopeptidase complex epsilon chain, Proteasome (prosome, macropain) subunit, beta type, 5, Proteasome beta 5 subunit, Proteasome catalytic subunit 3, Proteasome chain 6, Proteasome epsilon chain, Proteasome subunit beta type-5, Proteasome subunit MB1, Proteasome subunit X, Proteasome subunit, beta type, 5, Proteasome subunit, beta-5, PSB5_HUMAN, PSMB5, PSX large multifunctional protease X, X |