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TGFbeta RII polyclonal antibody

TGFbeta RII polyclonal antibody

ArtNr	BS7266-50
Hersteller	Bioworld Technology, Inc
Menge	50ul
Kategorie	Neuroscience Neuroinflammation Molecular Targets for Neuroscience Antibodies Cell Biology Cell Culture Cytokines Western Blot Immunofluorescence Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB, IF
Specific against	Human, Mouse, Rat
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	TGF-beta receptor type-2, TGFR-2, TGFR2, TGF-beta type II receptor, Transforming growth factor-beta receptor type II, TGF-beta receptor type II, TbetaR-II, TGFBR2
Similar products	TGFbeta RII
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Swiss-Prot	P37173
Application all	WB: 1:500ca.1:2000
Background	TGFbetas mediate their activity by high affinity binding to the type II receptor (TGFbeta RII) transmembrane protein with a cytoplasmic serine-threonine kinase domain. For signaling growth inhibition and early gene responses the type II receptor requires both its kinase activity and association with a TGFbeta-binding protein, designated the type I receptor. Two independent groups have recently described the cloning and sequence analysis of genes encoding TGFbeta type I receptor proteins designated ALK-5 (TbetaR-1) and TSR-1, respectively.
Product	1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Purification and Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Specificity	TGFbeta RII pAb detects endogenous levels of TGFbeta RII protein.
WB	Western blot (WB) analysis of TGFbeta RII polyclonal antibody
IHC	Immunohistochemistry (IHC) analysis of TGFbeta RII polyclonal antibody in paraffin-embedded Human Kidney Cancer tissue.
IF	Immunofluorescence analysis of U2OS cells, using TGFbeta RII polyclonal antibody
BiowMW	ca. 65 kDa
Note	For research use only, not for use in diagnostic procedure.
Alternative Name	TGF-beta receptor type-2, TGFR-2, TGFR2, TGF-beta type II receptor, Transforming growth factor-beta receptor type II, TGF-beta receptor type II, TbetaR-II, TGFBR2
Immunogen	Recombinant full length Human TGFbeta RII.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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