Hersteller |
Bioworld Technology, Inc
|
Kategorie |
|
Typ |
Antibody Polyclonal |
Specific against |
Human, Mouse, Rat |
Applikationen |
WB |
Menge |
50ul |
Host |
Rabbit |
ArtNr |
BS71024-50 |
Targets |
MAF ;;MAFB |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Lieferbar |
|
Alias |
Transcription factor MafB, Maf-B, V-maf musculoaponeurotic fibrosarcoma oncogene homolog B, MAFB, KRML |
Buffer composition |
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Background |
MafB is expressed in a wide variety of tissues and encodes a protein containing a typical bZip motif in its carboxy-terminal region. As a transcriptional activator, MafB plays a pivotal role in regulating lineage-specific gene expression during hematopoiesis by repressing Ets-1-mediated transcription of key erythroid-specific genes in myeloid cells. c-Maf interacts with the c-Myb DNA binding domain and forms Myb-Maf complexes, which inturn mediate the cooperative interactions between c-Myb and Ets-1 during early myeloid cell differentiation. |
Application info |
WB 1:500 - 1:2000 |
Swiss-Prot |
Q9Y5Q3 |
Purification and Purity |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). |
Storage and Stability |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Specificity |
MAFB polyclonal antibody detects endogenous levels of MAFB protein. |
BiowMW |
ca. 36 kDa |
Note |
For research use only, not for use in diagnostic procedure. |
Alternative Name |
Transcription factor MafB, Maf-B, V-maf musculoaponeurotic fibrosarcoma oncogene homolog B, MAFB, KRML |
Immunogen |
Recombinant protein of human MAFB. |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.