ArtNr |
BS7061-100 |
Hersteller |
Bioworld Technology, Inc
|
Menge |
100ul |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Matrix metalloproteinase-27, MMP-27, MMP27, UNQ2503/PRO5992 |
Similar products |
Cleaved-MMP-27 |
Lieferbar |
|
Swiss-Prot |
Q9H306 |
Application all |
WB: 1:500ca.1:1000 |
Background |
Metalloproteinases (MMPs) are a family of proteins that are involved in the breakdown of the extracellular matrix during normal cellular events, including reproduction, tissue remodeling and embryonic development. MMPs are crucial in tumor invasion and building of metastatic formations because of their ability to degrade extracellular matrix proteins such as fibronectin, laminin, gelatins and/or collagen. MMP-27 (matrix metallopeptidase 27) is a 513 amino acid secreted protein that is expressed in B-cells. Belonging to the peptidase M10A family, MMP-27 contains four hemopexin-like domains, which is suggested to be involved in substrate recognition. MMP-27, along with other MMP family members, is associated with breast cancer development and tumor progression. |
Product |
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. |
Purification and Purity |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). |
Storage and Stability |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Specificity |
Cleaved-MMP-27 (Y99) pAb detects endogenous levels of Cleaved-MMP-27 (45 kDa) protein. |
WB |
Western blot (WB) analysis of Cleaved-MMP-27 (Y99) pAb at 1:500 dilution Lane1:DLD cell lysate Lane2:Mouse kidney tissue lysate Lane3:Rat kidney tissue lysate |
BiowMW |
ca. 45, 59 kDa |
Note |
For research use only, not for use in diagnostic procedure. |
Alternative Name |
Matrix metalloproteinase-27, MMP-27, MMP27, UNQ2503/PRO5992 |
Immunogen |
Synthetic peptide, corresponding to amino acids 67-115 of Human Cleaved-MMP-27. |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.