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alpha-SMA polyclonal antibody

alpha-SMA polyclonal antibody

ArtNr	BS70000-100
Hersteller	Bioworld Technology, Inc
Menge	100ul
Kategorie	Neuroscience Protein Aggregation, Clearance & Misfolding Antibodies Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB, IF, IHC
Specific against	Human, Mouse, Rat
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ACTA2, AAT6, ACTSA, MYMY5, Actin, aortic smooth muscle, Alpha-actin-2, Cell growth-inhibiting gene 46 protein, alpha-SMA, a-SMA, aSMA, SMA-alpha
Similar products	alpha-SMA
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Swiss-Prot	P62736
Application all	WB: 1:500ca.1:1000 IHC: 1:50ca.1:200 IF: 1:50ca.1:200
Background	Defects in ACTA2 are the cause of aortic aneurysm familial thoracic type 6 (AAT6) [MIM:611788]. AATs are characterized by permanent dilation of the thoracic aorta usually due to degenerative changes in the aortic wall. They are primarily associated with a characteristic histologic appearance known as 'medial necrosis' or 'Erdheim cystic medial necrosis' in which there is degeneration and fragmentation of elastic fibers, loss of smooth muscle cells, and an accumulation of basophilic ground substance.
Product	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Purification and Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Specificity	alpha-SMA pAb detects endogenous levels of Actin, aortic smooth muscle protein.
WB	Western blot analysis on Jurkat cells using alpha-SMA pAb, The lane on the left is blocked with the antigen-specific peptide.
BiowMW	ca. 45 kDa
Note	For research use only, not for use in diagnostic procedure.
Alternative Name	ACTA2, AAT6, ACTSA, MYMY5, Actin, aortic smooth muscle, Alpha-actin-2, Cell growth-inhibiting gene 46 protein, alpha-SMA, a-SMA, aSMA, SMA-alpha
Immunogen	Recombinant full length Human alpha-SMA.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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