ArtNr |
BS6996-50 |
Hersteller |
Bioworld Technology, Inc
|
Menge |
50ul |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB, IF |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
ECLASS 5.1 |
32160702 |
ECLASS 6.1 |
32160702 |
ECLASS 8.0 |
32160702 |
ECLASS 9.0 |
32160702 |
ECLASS 10.0.1 |
32160702 |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Keratin, type II cytoskeletal 5, 58 kDa cytokeratin, Cytokeratin-5, Cytokeratin5, Short name=CK-5, CK5, Keratin-5, Keratin5, Keratin 5, Short name=K5, Type-II keratin Kb5, KRT5 |
Similar products |
Cytokeratin 5 |
Lieferbar |
|
Swiss-Prot |
P13647 |
Application all |
WB: 1:500ca.1:2000 |
Background |
Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratins have been found to be useful markers of tissue differentiation which is directly applicable to the characterization of malignant tumors. Cytokeratin 5 is expressed in normal basal cells. Mutations of the Cytokeratin 5 gene (KRT5) have been shown to result in the autosomal dominant disorder epidermolysis bullosa (EB). |
Product |
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. |
Purification and Purity |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). |
Storage and Stability |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Specificity |
Cytokeratin 5 pAb detects endogenous levels of Cytokeratin 5 protein. |
WB |
Western blot analysis of Cytokeratin 5 polyclonal antibody |
IF |
Immunofluorescence analysis of Hela cells, using Cytokeratin 5 polyclonal antibody |
BiowMW |
ca. 62 kDa |
Note |
For research use only, not for use in diagnostic procedure. |
Alternative Name |
Keratin, type II cytoskeletal 5, 58 kDa cytokeratin, Cytokeratin-5, Cytokeratin5, Short name=CK-5, CK5, Keratin-5, Keratin5, Keratin 5, Short name=K5, Type-II keratin Kb5, KRT5 |
Immunogen |
Recombinant full length Human Cytokeratin 5. |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.