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MEK-4/ MAP2K4 (phospho-T261) polyclonal antibody

MEK-4/ MAP2K4 (phospho-T261) polyclonal antibody

ArtNr	BS6395-100
Hersteller	Bioworld Technology, Inc
Menge	100ul
Kategorie	Neuroscience Molecular Targets for Neuroscience Neural Signaling Antibodies Cell Biology Cell Status Western Blot Senescence Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB
Specific against	Human, Mouse, Rat
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Dual specificity mitogen-activated protein kinase kinase 4, MAP kinase kinase 4, MAPKK 4, JNK-activating kinase 1, MAPK/ERK kinase 4, MEK 4, SAPK/ERK kinase 1, SEK1, Stress-activated protein kinase kinase 1, SAPK kinase 1, SAPKK-1, SAPKK1, c-Jun N-termina
Similar products	MEK-4/ MAP2K4
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Swiss-Prot	P45985
Application all	WB: 1:500ca.1:2000
Background	The prototype member of this family, designated MAP kinase kinase, or MEK-1, specifically phosphorylates the MAP kinase regulatory threonine and tyrosine residues present in the Thr-Glu-Tyr motif of ERK. A second MEK family member, MEK-2, resembles MEK-1 in its substrate specificity. MEK-3 (or MKK-3) functions to activate p38 MAP kinase, and MEK-4 (also called SEK1 or MKK-4) activates both p38 and JNK MAP kinases. MEK-5 appears to specifically phosphorylate ERK 5, whereas MEK-6 phosphorylates p38 and p38beta. MEK-7 (or MKK-7) phosphorylates and activates the JNK signal transduction pathway.
Product	1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Purification and Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Specificity	P-MAP2K4(T261) pAb detects endogenous levels of MAP2K4 protein only when phosphorylated at Thr261.
BiowMW	ca. 44 kDa
Note	For research use only, not for use in diagnostic procedure.
Alternative Name	Dual specificity mitogen-activated protein kinase kinase 4, MAP kinase kinase 4, MAPKK 4, JNK-activating kinase 1, MAPK/ERK kinase 4, MEK 4, SAPK/ERK kinase 1, SEK1, Stress-activated protein kinase kinase 1, SAPK kinase 1, SAPKK-1, SAPKK1, c-Jun N-terminal kinase kinase 1, JNKK, MAP2K4, JNKK1, MEK4, MKK4, , PRKMK4, SEK1, SERK1, SKK1
Immunogen	Synthetic phosphopeptide derived from human MEK-4 around the phosphorylation site of Threonine 261.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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