IL9 polyclonal antibody

P15248

Interleukin-9, or IL-9, is a TH2 cytokine that has been shown to promote the antigen-independent growth of some T helper clones. IL-9 is a pleiotropic cytokine with multiple functions on cells of lymphoid, myeloid and mast cell lineages. Both mouse and human cDNAs encode 144 amino acid precursors with 18 amino acid residue signal peptides that are cleaved to form the mature biologically active glycoprotein. Although IL-9 is constitutively expressed in vitro by several transformed T cell lines, IL-9 expression can be induced in human peripheral blood T lymphocytes by T cell activators such as phorbol esters (PHA) and anti-CD3 antibodies. IL-9 exerts its biological effects through the interleukin-9 receptor, IL-9R. IL-9R is composed of at least two subunits: t

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

IL9 pAb detects endogenous levels of IL9 protein.

ca. 15 kDa

Interleukin-9, IL-9, Cytokine P40, T-cell growth factor P40, IL9