Hersteller |
Bioworld Technology, Inc
|
Kategorie |
|
Typ |
Antibody Polyclonal |
Specific against |
Human, Mouse, Rat |
Applikationen |
WB |
Menge |
50ul |
Host |
Rabbit |
ArtNr |
BS60234-50 |
Targets |
RHOF |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Lieferbar |
|
Alias |
Rho-related GTP-binding protein RhoF, Rho family GTPase Rif, Rho in filopodia, RHOF, ARHF, RIF |
Swiss-Prot |
Q9HBH0 |
Application all |
WB: 1:500ca.1:1000 |
Background |
Rho, the Ras-related small GTPase, is responsible for the regulation of actin-based cytoskeletal structures including stress fibers, focal adhesions and the contractile ring apparatus. Rho proteins function as molecular switches that are able to turn cytokinesis on and off. Although little is known about signaling downstream of Rho, a host of putative Rho effector proteins have been described. Rho F (ras homolog gene family, member F), also known as RIF or ARHF, is a 211 amino acid membrane protein that localizes to the cytoplasmic side of the plasma membrane. Belonging to the small GTPase superfamily and the Rho family, Rho F functions cooperatively with Cdc42 and Rac to generate additional cytoskeletal structures, such as increasing variation of actin-based morphology. Rho F exists as two alternatively spliced isoforms and is encoded by a gene located on human chromosome 12q24.31. |
Product |
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. |
Purification and Purity |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). |
Storage and Stability |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Specificity |
RHOF pAb detects endogenous levels of RHOF protein. |
WB |
Western blot (WB) analysis of RHOF pAb at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:Raw264.7 whole cell lysate Lane3:H9C2 whole cell lysate |
BiowMW |
ca. 24 kDa |
Note |
For research use only, not for use in diagnostic procedure. |
Alternative Name |
Rho-related GTP-binding protein RhoF, Rho family GTPase Rif, Rho in filopodia, RHOF, ARHF, RIF |
Immunogen |
A synthetic peptide corresponding to residues in Human RHOF |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.