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TADA2L polyclonal antibody

ArtNr BS5953-50
Hersteller Bioworld Technology, Inc
Menge 50ul
Kategorie
Typ Antibody Polyclonal
Applikationen WB, ICC
Specific against Human, Mouse, Rat
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Transcriptional adapter 2-alpha, Transcriptional adapter 2-like, ADA2-like protein, TADA2A, TADA2L, KL04P
Similar products TADA2L
Lieferbar
Swiss-Prot
O75478
Application all
WB: 1:500ca.1:1000
ICC: 1:50ca.1:200
Background
TADA2L (transcriptional adapter 2-like), also known as TADA2A (transcriptional adapter 2-alpha) or ADA2-like protein, is a 443 amino acid nuclear protein that exists as 2 alternatively spliced isoforms. While most abundantly expressed in testis, TADA2L is present in all tissues. TADA2L contains one SANT domain and one SWIRM domain, and interacts with GCN5 and GR (NR3C1). Its ability to bind double-stranded DNA allows TADA2L to play a role in chromatin remodeling. Although it makes up part of the PCAF complex, TADA2L is also a component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. The gene that encodes TADA2L contains 71, 408 bases and maps to human chromosome 17q12. Chromosome 7 houses over 1, 000 genes, comprises nearly 5% of the human genome and has been linked to osteogenesis imperfecta, Pendred syndrome, lissencephaly, citrullinemia and Shwachman-Diamond syndrome.
Product
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Purification and Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Specificity
TADA2L pAb detects endogenous levels of TADA2L protein.
WB
Western blot (WB) analysis of TADA2L pAb at 1:500 dilution
Lane1:MCF-7 cell lysate
Lane2:sp2/0 cell lysate
Lane3:H9C2 cell lysate
BiowMW
ca. 51 kDa
Note
For research use only, not for use in diagnostic procedure.
Alternative Name
Transcriptional adapter 2-alpha, Transcriptional adapter 2-like, ADA2-like protein, TADA2A, TADA2L, KL04P
Immunogen
Synthetic peptide, corresponding to amino acids 248-293 of Human TADA2L.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50ul
Lieferbar: In stock
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