ArtNr |
BS5939-50 |
Hersteller |
Bioworld Technology, Inc
|
Menge |
50ul |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB, IHC, ICC |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
116 kDa U5 small nuclear ribonucleoprotein component, Elongation factor Tu GTP-binding domain-containing protein 2, SNU114 homolog, Hsnu114, U5 snRNP-specific protein, 116 kDa, U5-116 kDa, KIAA0031, SNRP116 |
Similar products |
EFTUD2 |
Lieferbar |
|
Swiss-Prot |
Q15029 |
Application all |
WB: 1:500ca.1:1000 IHC: 1:50ca.1:200 ICC: 1:50ca.1:200 |
Background |
Spliceosomes are multi-protein complexes that are composed of snRNPs (small nuclear ribonucleoproteins) and a variety of associated protein factors, all of which work in concert to regulate the splicing of pre-mRNA. Snrp116, also known as EFTUD2 (elongation factor Tu GTP binding domain containing 2) or Snu114, is a 972 amino acid protein that localizes to the nucleus and belongs to the GTP-binding elongation factor family. Existing as a component of the multi-protein U5 snRNP spliceosome complex, Snrp116 plays an important role in pre-mRNA splicing, as well as in the recycling of spliceosomal snRNPs. The gene encoding Snrp116 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1, 200 genes. |
Product |
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. |
Purification and Purity |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). |
Storage and Stability |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Specificity |
EFTUD2 pAb detects endogenous levels of EFTUD2 protein. |
WB |
Western blot (WB) analysis of EFTUD2 pAb at 1:500 dilution Lane1:MCF-7 cell lysate Lane2:sp2/0 cell lysate Lane3:H9C2 cell lysate |
BiowMW |
ca. 116 kDa |
Note |
For research use only, not for use in diagnostic procedure. |
Alternative Name |
116 kDa U5 small nuclear ribonucleoprotein component, Elongation factor Tu GTP-binding domain-containing protein 2, SNU114 homolog, Hsnu114, U5 snRNP-specific protein, 116 kDa, U5-116 kDa, KIAA0031, SNRP116 |
Immunogen |
Synthetic peptide, corresponding to amino acids 371-416 of Human EFTUD2. |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.