MYL9 (phospho-S19) polyclonal antibody

Myosin regulatory light chains, including MRCL3 (also known as MRLC3 or MLCB), MRLC2 (also known as MLC-B) and MYL9 (also known as LC20, MLC2, MRLC1 or MYRL2), regulate contraction in smooth muscle and non-muscle cells via phosphorylation by myosin light chain kinase (MLCK). Phosphorylation of myosin regulatory light chains, catalyzed by MLCK in the presence of calcium and calmodulin, increases the Actin-activated myosin ATPase activity, thereby regulating the contractile activity. Myosin light chain is also located in striated skeletal muscle, where its function remains undefined.

p-MYL9 (S19) polyclonal antibody detects endogenous levels of MYL9 protein only when phosphorylated at Ser19. This antibody may detects endogenous levels of MYL12A protein only when phosphorylated at Ser18.

For research use only, not for use in diagnostic procedure.

Phosphorylation