ArtNr |
BS4673-100 |
Hersteller |
Bioworld Technology, Inc
|
Menge |
100ul |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Tyrosine-protein kinase CSK, C-Src kinase, Protein-tyrosine kinase CYL, CSK |
Similar products |
Csk |
Lieferbar |
|
Swiss-Prot |
P41240 |
Application all |
WB: 1:500ca.1:1000 |
Background |
C terminal Src kinase (CSK) is a non receptor protein tyrosine kinase. One of its major functions is to specifically phosphorylate a conserved C terminal tyrosine of Src family kinases thereby down regulating their kinase activity. CSK is expressed ubiquitously as a protein of approximately 50 KDa in cytosol, but a fraction distributes to lipid rafts due to interaction with the lipid raft associated protein PAG (CSK binding protein). |
Product |
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. |
Purification and Purity |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). |
Storage and Stability |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Specificity |
p-Csk (S364) pAb detects endogenous levels of Csk protein when phosphorylated at Ser364. |
WB |
Western blot (WB) analysis of p-CSK (S364) pAb at 1:500 dilution Lane1:HEK293T cell lysate treated with PMA(100nM, 15min) Lane2:NIH-3T3 cell lysate treated with PMA(100nM, 15min) Lane3:H9C2 cell lysate treated with PMA(100nM, 15min) |
BiowMW |
ca. 50 kDa |
Note |
For research use only, not for use in diagnostic procedure. |
Alternative Name |
Tyrosine-protein kinase CSK, C-Src kinase, Protein-tyrosine kinase CYL, CSK |
Immunogen |
Synthetic phosphopeptide derived from human Csk around the phosphorylation site of Serine 364. |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.