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TRP2 (K89) polyclonal antibody

TRP2 (K89) polyclonal antibody

Hersteller	Bioworld Technology, Inc
Kategorie	Neuroscience Neuroinflammation Metabolism Diabetes Antibodies Western Blot Immunofluorescence Primary Antibodies
Typ	Antibody Polyclonal
Specific against	Human, Mouse, Rat
Applikationen	WB, IF
Menge	100ul
Host	Rabbit
ArtNr	BS3320-100
Targets	MIF ;; TYR ;;RANBP2
eClass 6.1	32160702
eClass 9.0	32160702
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Alias	DCT, TYRP2, L-dopachrome tautomerase, TRP-2, TRP2, Tyrosinase-related protein 2,
Swiss-Prot	P40126
Application all	WB: 1:500ca.1:1000 IF: 1:50ca.1:200
Background	The TYR-related proteins, TRP1 and TRP2, are also specifically expressed in melanocytes, and they likewise contribute to the synthesis of melanin within the melanosomes. The TRPs, including TYR, all share a similar transmembrane region, contain two metal-binding regions and a cysteinerich epidermal growth factor motif, and are localized in the melanosomal membrane. These proteins, however, have distinct catalytic activity, and they individually contribute to the biosynthesis of melanin biopolymers. The TRPs are believed to exist as a multi-enzyme complex, as these proteins form aggregates together, and the expression of TRP1 also helps stabilize TYR in melanocytes.
Product	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Purification and Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Specificity	TRP2 (K89) pAb detects endogenous levels of TRP2 protein.
WB	Western blot (WB) analysis of TRP2 (K89) pAb at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:sp2/0 whole cell lysate Lane3:PC12 whole cell lysate
BiowMW	ca. 60 kDa
Note	For research use only, not for use in diagnostic procedure.
Alternative Name	DCT, TYRP2, L-dopachrome tautomerase, TRP-2, TRP2, Tyrosinase-related protein 2,
Immunogen	Synthetic peptide, corresponding to amino acids 50-100 of Human TRP2.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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