ArtNr |
BS3287-100 |
Hersteller |
Bioworld Technology, Inc
|
Menge |
100ul |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB, IHC |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
ECLASS 5.1 |
32160702 |
ECLASS 6.1 |
32160702 |
ECLASS 8.0 |
32160702 |
ECLASS 9.0 |
32160702 |
ECLASS 10.0.1 |
32160702 |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Coatomer subunit zeta-1, Zeta-1-coat protein, Zeta-1 COP, COPZ1, COPZ, CGI-120, HSPC181, COP zeta-1 |
Similar products |
COP zeta1 |
Lieferbar |
|
Swiss-Prot |
P61923 |
Application all |
WB: 1:500ca.1:1000 IHC: 1:50ca.1:200 |
Background |
Membrane and vesicular trafficking in the early secretory pathway are mediated by non-Clathrin COP (coat protein) I-coated vesicles. COPI-coated vesicles mediate retrograde transport from the Golgi back to the ER and intra-Golgi transport. The cytosolic precursor of the COPI coat, the heptameric coatomer complex, is composed of two subcomplexes. The first consists of the COPB, COPG, COPD and COPZ1 subunits (also known as beta-COP, gamma-COP, delta-COP and zeta-1 COP, respectively), which are distantly homologous to AP Clathrin adaptor subunits. The second consists of the COPA, COPP and COPE subunits (also known as alpha-COP, COPP and epsilon-COP, respectively). |
Product |
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. |
Purification and Purity |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). |
Storage and Stability |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Specificity |
COP zeta1 (I48) pAb detects endogenous levels of COP zeta1 protein. |
WB |
Western blot (WB) analysis of COP zeta1 (I48) pAb at 1:500 dilution Lane1:Hela cell lysate Lane2:HEK293T cell lysate Lane3:sp2/0 cell lysate Lane4:H9C2 cell lysate Lane5:PC12 cell lysate |
IHC |
Immunohistochemistry (IHC) analyzes of COP zeta1 (I48) pAb in paraffin-embedded human cervix carcinoma tissue. |
BiowMW |
ca. 20 kDa |
Note |
For research use only, not for use in diagnostic procedure. |
Alternative Name |
Coatomer subunit zeta-1, Zeta-1-coat protein, Zeta-1 COP, COPZ1, COPZ, CGI-120, HSPC181, COP zeta-1 |
Immunogen |
Synthetic peptide, corresponding to the N-terminus of Human COP zeta1. |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.