ArtNr |
BS3158-100 |
Hersteller |
Bioworld Technology, Inc
|
Menge |
100ul |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Beta-3 adrenergic receptor, Beta-3 adrenoreceptor, Beta-3 adrenoceptor, ADRB3, ADRB3R, B3AR, AR beta3, ARbeta3, beta3-AR, beta3 AR, beta3AR |
Similar products |
AR-beta3 |
Lieferbar |
|
Swiss-Prot |
P13945 |
Application all |
WB: 1:500ca.1:1000 |
Background |
Beta 3-adrenergic receptors (b3-ARs) bind cathecholamines (epinephrine, norepinephrine), and primarily regulate lipolysis and thermogenesis in adipose. b3-ARs are present in adipose tissues, heart, and in smooth muscle of bladder, colon, small intestine, and stomach. The human corpus cavernosum exhibits basal b3-AR-mediated vasorelaxant tone and activity is linked to inhibition of the RhoA/Rho-kinase pathway. b3-AR interacts directly with the SH3 domain of Src through proline-rich motifs (PXXP) in the third intracellular loop and the carboxy-terminus. |
Product |
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. |
Purification and Purity |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). |
Storage and Stability |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Specificity |
AR-beta3 (L291) pAb detects endogenous levels of AR-beta3 protein. |
WB |
Western blot (WB) analysis of AR-beta3 (L291) pAb at 1:500 dilution Lane1:MCF-7 cell lysate Lane2:Mouse kidney tissue lysate Lane3:Rat liver tissue lysate |
BiowMW |
ca. 43, 68 kDa |
Note |
For research use only, not for use in diagnostic procedure. |
Alternative Name |
Beta-3 adrenergic receptor, Beta-3 adrenoreceptor, Beta-3 adrenoceptor, ADRB3, ADRB3R, B3AR, AR beta3, ARbeta3, beta3-AR, beta3 AR, beta3AR |
Immunogen |
Synthetic peptide, corresponding to amino acids 250-300 of Human AR-beta3. |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.