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HSPB2 (N143) polyclonal antibody

HSPB2 (N143) polyclonal antibody

ArtNr	BS3031-100
Hersteller	Bioworld Technology, Inc
Menge	100ul
Kategorie	Antibodies Immunohistochemistry Western Blot Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB, IHC
Specific against	Human, Mouse, Rat
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Heat shock protein beta-2, HspB2, DMPK-binding protein, MKBP, HSPB2
Similar products	HSPB2
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Swiss-Prot	Q16082
Application all	WB: 1:500ca.1:1000 IHC: 1:50ca.1:200
Background	HSPB2, also called MKBP, was shown to bind and activate myotonic dystrophy protein kinase in the yeast two-hybrid system. The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The protein is expressed preferentially in the heart and skeletal muscle. This protein regulates Myotonic Dystrophy Protein Kinase, which plays an important role in maintenance of muscle structure and function.
Product	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Purification and Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Specificity	HSPB2 (N143) pAb detects endogenous levels of HSPB2 protein.
WB	Western blot (WB) analysis of HSPB2 (N143) pAb at 1:500 dilution Lane1:Jurkat whole cell lysate Lane2:Raw264.7 whole cell lysate Lane3:H9C2 whole cell lysate
IHC	Immunohistochemistry (IHC) analyzes of HSPB2 (N143) pAb in paraffin-embedded human tonsil carcinoma tissue at 1:50.
BiowMW	ca. 20 kDa
Note	For research use only, not for use in diagnostic procedure.
Alternative Name	Heat shock protein beta-2, HspB2, DMPK-binding protein, MKBP, HSPB2
Immunogen	Synthetic peptide, corresponding to amino acids 110-168 of Human HSPB2.

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