Hersteller |
Bioworld Technology, Inc
|
Kategorie |
|
Typ |
Antibody Polyclonal |
Specific against |
Human, Mouse, Rat |
Applikationen |
WB, IHC |
Menge |
100ul |
Host |
Rabbit |
ArtNr |
BS2667-100 |
Targets |
TFAP2A |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Lieferbar |
|
Alias |
Transcription factor AP-2 gamma, AP2-gamma, Activating enhancer-binding protein 2 gamma, Transcription factor ERF-1, TFAP2C, AP2-gamma, AP 2gamma, AP2gamma, AP-2gamma |
Swiss-Prot |
Q92754 |
Application all |
WB: 1:500ca.1:1000 IHC: 1:50ca.1:200 |
Background |
AP2 gamma is a sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. |
Product |
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. |
Purification and Purity |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). |
Storage and Stability |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Specificity |
AP-2gamma (A436) pAb detects endogenous levels of AP-2gamma protein. |
WB |
Western blot (WB) analysis of AP-2gamma (A436) pAb at 1:500 dilution Lane1:Hela cell lysate Lane2:Raw264.7 cell lysate Lane3:PC12 cell lysate |
BiowMW |
ca. 45 kDa |
Note |
For research use only, not for use in diagnostic procedure. |
Alternative Name |
Transcription factor AP-2 gamma, AP2-gamma, Activating enhancer-binding protein 2 gamma, Transcription factor ERF-1, TFAP2C, AP2-gamma, AP 2gamma, AP2gamma, AP-2gamma |
Immunogen |
Synthetic peptide, corresponding to amino acids 400-448 of Human AP-2gamma. |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.