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CRF-RII (H112) polyclonal antibody

CRF-RII (H112) polyclonal antibody

ArtNr	BS2616-100
Hersteller	Bioworld Technology, Inc
Menge	100ul
Kategorie	Neuroscience Neuroinflammation Metabolism Glucose Homeostasis Antibodies Western Blot Immunofluorescence Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB, IF
Specific against	Human, Mouse, Rat
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Corticotropin-releasing factor receptor 2, CRF-R-2, CRF-R2, CRFR-2, Corticotropin-releasing hormone receptor 2, CRH-R-2, CRH-R2, CRF2R, CRH2R, CRHR2
Similar products	CRF-RII
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Swiss-Prot	Q13324
Application all	WB: 1:500ca.1:1000 IF: 1:50ca.1:200
Background	Two CRF receptors, designated CRF-RI and CFR-RII, exhibit distinct brain localizations.Two forms of CFR-RII, designated CFR-RIIalpha and CFR-RIIbeta, result from alternative mRNA splicing. Urocortin, an additional member of the CRF family, shares 63% sequence identity with urotensin and 45% sequence identity with CRF. Urocortin specifically binds to and activates CRF-RI and CRF-RII, but binds to CRF-RII more efficiently than CRF, suggesting that it may be the true, high affinity ligand for the CRF receptor type II.
Product	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Purification and Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Specificity	CRF-RII (H112) pAb detects endogenous levels of CRF-RII protein.
WB	Western blot (WB) analysis of CRF-RII (H112) pAb at 1:500 dilution Lane1:Hela cell lysate Lane2:sp2/0 cell lysate Lane3:H9C2 cell lysate
BiowMW	ca. 48 kDa
Note	For research use only, not for use in diagnostic procedure.
Alternative Name	Corticotropin-releasing factor receptor 2, CRF-R-2, CRF-R2, CRFR-2, Corticotropin-releasing hormone receptor 2, CRH-R-2, CRH-R2, CRF2R, CRH2R, CRHR2
Immunogen	Synthetic peptide, corresponding to amino acids 96-85 of Human CRF-RII.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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