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ChoKB (E324) polyclonal antibody

ArtNr BS2377-50
Hersteller Bioworld Technology, Inc
Menge 50 ul
Quantity options 100 ul 50 ul
Kategorie
Typ Antibody Polyclonal
Applikationen WB, IHC
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Konjugat/Tag Unconjugated
Purity The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Choline/ethanolamine kinase, Choline kinase beta, Short name=CK, CKB, Choline kinase-like protein, Ethanolamine kinase, Short name=EK, Ethanolamine kinase beta, EKB, choline/ethanolamine kinase beta, CKEKB, CHKB, CHETK, CHKL
Similar products ChoKB
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Application Notes
IHC: 1:50~1:200
Background
The major pathway for the biosynthesis of phosphatidylcholine occurs via the CDP-choline pathway. Choline kinase, the initial enzyme in the sequence, plays a role in cell growth proliferation. A related protein, ChoKB (also, known as choline kinase beta), is a 395 amino acid enzyme that catalyzes the phosphorylation of choline by ATP in the presence of magnesium, thereby yielding phosphocholine and ADP. Like all choline kinases, ChoKB possesses ethanoalamine kinase activity and catalyzes the phosphorylation of ethanolamine. The gene encoding ChoKB is located less than 1 kb upstream of the CPT1B gene, suggesting that the ChoKB gene may regulate transcription CPT1B. In mice, mutations and/or deletions in the gene encoding ChoKB are the cause of hindlimb muscular dystrophy and neonatal bone deformity.
Manufacturer - Product
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Manufacturer - Specificity
ChoKB (E324) polyclonal antibody detects endogenous levels of ChoKB protein.
Molecular Weight
~ 45 kDa
Note
For research use only, not for use in diagnostic procedure.
Immunogen
Synthetic peptide, corresponding to amino acids 300-342 of Human ChoKB.
Modification
Unmodification

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ul
Lieferbar: In stock
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