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STAG3 (Q1187) polyclonal antibody

STAG3 (Q1187) polyclonal antibody

ArtNr	BS2375-50
Hersteller	Bioworld Technology, Inc
Menge	50ul
Kategorie	Antibodies Immunohistochemistry Western Blot Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB, IHC
Specific against	Human, Mouse, Rat
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Cohesin subunit SA-3, SCC3 homolog 3, Stromal antigen 3, Stromalin-3, STAG3
Similar products	STAG3
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Swiss-Prot	Q9UJ98
Application all	WB: 1:500ca.1:1000 IHC: 1:50ca.1:200
Background	Stromalins are a group of highly conserved proteins that are characterized by the stromalin conservative domain. Stromal antigen 3 (STAG3) is a nuclear protein that is expressed specifically in germinal cells. STAG3 associates with the synaptonemal complex (SC) via immunolocalization. The SC is a meiotic protein structure that aids in the pairing of homologous chromosomes. In mammals, STAG3 associates with the SC and assists in sister chromatid cohesion, which keeps the homologous chromosomes appropriately aligned during the pachytene stage of prophase I. STAG3 appears to be located at the interchromatid domain during metaphase I, but is undetectable in ana-phase I or any of the later stages of meiosis.
Product	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Purification and Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Specificity	STAG3 (Q1187) pAb detects endogenous levels of STAG3 protein.
WB	Western blot (WB) analysis of STAG3 (Q1187) pAb at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:sp2/0 whole cell lysate Lane3:PC12 whole cell lysate
IHC	Immunohistochemistry (IHC) analyzes of STAG3 (Q1187) pAb in paraffin-embedded human testis tissue.
BiowMW	ca. 139 kDa
Note	For research use only, not for use in diagnostic procedure.
Alternative Name	Cohesin subunit SA-3, SCC3 homolog 3, Stromal antigen 3, Stromalin-3, STAG3
Immunogen	Synthetic peptide, corresponding to amino acids 1156-1200 of Human STAG3.

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