ArtNr |
BS2375-50 |
Hersteller |
Bioworld Technology, Inc
|
Menge |
50ul |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB, IHC |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Cohesin subunit SA-3, SCC3 homolog 3, Stromal antigen 3, Stromalin-3, STAG3 |
Similar products |
STAG3 |
Lieferbar |
|
Swiss-Prot |
Q9UJ98 |
Application all |
WB: 1:500ca.1:1000 IHC: 1:50ca.1:200 |
Background |
Stromalins are a group of highly conserved proteins that are characterized by the stromalin conservative domain. Stromal antigen 3 (STAG3) is a nuclear protein that is expressed specifically in germinal cells. STAG3 associates with the synaptonemal complex (SC) via immunolocalization. The SC is a meiotic protein structure that aids in the pairing of homologous chromosomes. In mammals, STAG3 associates with the SC and assists in sister chromatid cohesion, which keeps the homologous chromosomes appropriately aligned during the pachytene stage of prophase I. STAG3 appears to be located at the interchromatid domain during metaphase I, but is undetectable in ana-phase I or any of the later stages of meiosis. |
Product |
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. |
Purification and Purity |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). |
Storage and Stability |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Specificity |
STAG3 (Q1187) pAb detects endogenous levels of STAG3 protein. |
WB |
Western blot (WB) analysis of STAG3 (Q1187) pAb at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:sp2/0 whole cell lysate Lane3:PC12 whole cell lysate |
IHC |
Immunohistochemistry (IHC) analyzes of STAG3 (Q1187) pAb in paraffin-embedded human testis tissue. |
BiowMW |
ca. 139 kDa |
Note |
For research use only, not for use in diagnostic procedure. |
Alternative Name |
Cohesin subunit SA-3, SCC3 homolog 3, Stromal antigen 3, Stromalin-3, STAG3 |
Immunogen |
Synthetic peptide, corresponding to amino acids 1156-1200 of Human STAG3. |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.