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RORalpha (G41) polyclonal antibody

ArtNr BS2272-50
Hersteller Bioworld Technology, Inc
Menge 50ul
Kategorie
Typ Antibody Polyclonal
Applikationen WB, IF, IHC
Specific against Human, Mouse, Rat
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Nuclear receptor ROR-alpha, Nuclear receptor RZR-alpha, Nuclear receptor subfamily 1 group F member 1, Retinoid-related orphan receptor-alpha, RORA, NR1F1, RZRA
Similar products RORalpha
Lieferbar
Swiss-Prot
P35398
Application all
WB: 1:500ca.1:1000
IHC: 1:50ca.1:200
IF: 1:50ca.1:200
Background
Retinoid related orphan receptor alpha (ROR alpha) is a NR1 Thyroid Hormone Like Receptor. To date, ROR alpha, beta, and gamma subtypes have been discovered. ROR alpha has been shown to affect the development of the central nervous system. Deletion of ROR alpha in mice causes severe impairment in the differentiation of cerebellar Purkinje neurons and results in the "staggerer" phenotype. ROR alpha has been suggested as a potential target in the treatment of chronic inflammatory diseases, including atherosclerosis and rheumatoid arthritis.
Product
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Purification and Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Specificity
RORalpha (G41) pAb detects endogenous levels of RORalpha protein.
WB
Western blot (WB) analysis of RORalpha (G41) pAb at 1:500 dilution
Lane1:HEK293T whole cell lysate
Lane2:Raw264.7 whole cell lysate
Lane3:H9C2 whole cell lysate
IHC
Immunohistochemistry (IHC) analyzes of RORalpha (G41) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.
BiowMW
ca. 60 kDa
Note
For research use only, not for use in diagnostic procedure.
Alternative Name
Nuclear receptor ROR-alpha, Nuclear receptor RZR-alpha, Nuclear receptor subfamily 1 group F member 1, Retinoid-related orphan receptor-alpha, RORA, NR1F1, RZRA
Immunogen
Synthetic peptide, corresponding to amino acids 20-70 of Human RORalpha.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50ul
Lieferbar: In stock
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