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IL-2Rbeta (T360) polyclonal antibody

IL-2Rbeta (T360) polyclonal antibody

ArtNr	BS1668-50
Hersteller	Bioworld Technology, Inc
Menge	50ul
Kategorie	Neuroscience Neural Lineage Markers Antibodies Cell Biology Cell Culture Cytokines Immunohistochemistry Western Blot Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB, IHC
Specific against	Human, Mouse, Rat
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Interleukin-2 receptor subunit beta, IL-2 receptor subunit beta, IL-2R subunit beta, IL-2RB, High affinity IL-2 receptor subunit beta, p70-75, Short name=p75, CD122, IL2RB
Similar products	IL-2Rbeta
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Swiss-Prot	P14784
Application all	WB: 1:500ca.1:1000 IHC: 1:50ca.1:200
Background	The Interleukin 2 Receptor alpha and beta chains, together with the common gamma chain, constitute the high affinity IL2 receptor present on activated T and B cells, thymocyte subset, pre B cells and T regulatory cells. Homodimeric alpha chains result in low affinity receptor, while homodimeric beta chains produce a medium affinity receptor. Normally an integral membrane protein, soluble IL2 Receptor alpha has been isolated and determined to result from extracellular proteolysis. Alternately spliced IL2 Receptor alpha mRNAs have been isolated, but the significance of each is presently unknown.
Product	1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
Purification and Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Specificity	IL-2Rbeta (T360) pAb detects endogenous levels of IL-2Rbeta protein.
WB	Western blot (WB) analysis of IL-2Rbeta (T360) pAb in extracts from PC12 cells.
IHC	Immunohistochemistry (IHC) analyzes of IL-2Rbeta (T360) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.
BiowMW	ca.60 kDa
Note	For research use only, not for use in diagnostic procedure.
Alternative Name	Interleukin-2 receptor subunit beta, IL-2 receptor subunit beta, IL-2R subunit beta, IL-2RB, High affinity IL-2 receptor subunit beta, p70-75, Short name=p75, CD122, IL2RB
Immunogen	Synthetic peptide, corresponding to amino acids 330-380 of Human IL-2Rbeta.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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