ArtNr |
BS1208-100 |
Hersteller |
Bioworld Technology, Inc
|
Menge |
100 ul |
Quantity options |
100 ul
50 ul
|
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB, IF, IHC |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Konjugat/Tag |
Unconjugated |
Purity |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Keratin, type II cytoskeletal 5, 58 kDa cytokeratin, Cytokeratin-5, Cytokeratin5, Short name=CK-5, CK5, Keratin-5, Keratin5, Keratin 5, Short name=K5, Type-II keratin Kb5, KRT5 |
Similar products |
Cytokeratin 5 |
Lieferbar |
|
Application Notes |
WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200 |
Background |
Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratins have been found to be useful markers of tissue differentiation which is directly applicable to the characterization of malignant tumors. Cytokeratin 5 is expressed in normal basal cells. Mutations of the Cytokeratin 5 gene (KRT5) have been shown to result in the autosomal dominant disorder epidermolysis bullosa (EB). |
Manufacturer - Product |
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 |
Manufacturer - Specificity |
Cytokeratin 5 (S573) polyclonal antibody detects endogenous levels of Cytokeratin 5 protein. |
Molecular Weight |
~ 62 kDa |
Note |
For research use only, not for use in diagnostic procedure. |
Pathway |
Contribution of Soluble Factors to EMT |
Immunogen |
Synthetic peptide, corresponding to amino acids 550-600 of Human Cytokeratin 5. |
Modification |
Unmodification |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.