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Cytokeratin 5 (S573) polyclonal antibody

Cytokeratin 5 (S573) polyclonal antibody

ArtNr	BS1208-100
Hersteller	Bioworld Technology, Inc
Menge	100 ul
Quantity options	100 ul 50 ul
Kategorie	Oncology Antibodies Cell Biology Cytoskeleton Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies Intermediate filaments By Organ Breast Cancer
Typ	Antibody Polyclonal
Applikationen	WB, IF, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Konjugat/Tag	Unconjugated
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Keratin, type II cytoskeletal 5, 58 kDa cytokeratin, Cytokeratin-5, Cytokeratin5, Short name=CK-5, CK5, Keratin-5, Keratin5, Keratin 5, Short name=K5, Type-II keratin Kb5, KRT5
Similar products	Cytokeratin 5
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Application Notes	WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200
Background	Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratins have been found to be useful markers of tissue differentiation which is directly applicable to the characterization of malignant tumors. Cytokeratin 5 is expressed in normal basal cells. Mutations of the Cytokeratin 5 gene (KRT5) have been shown to result in the autosomal dominant disorder epidermolysis bullosa (EB).
Manufacturer - Product	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Manufacturer - Specificity	Cytokeratin 5 (S573) polyclonal antibody detects endogenous levels of Cytokeratin 5 protein.
Molecular Weight	~ 62 kDa
Note	For research use only, not for use in diagnostic procedure.
Pathway	Contribution of Soluble Factors to EMT
Immunogen	Synthetic peptide, corresponding to amino acids 550-600 of Human Cytokeratin 5.
Modification	Unmodification

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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