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HDAC5 (E1106) polyclonal antibody

ArtNr BS1163-50
Hersteller Bioworld Technology, Inc
Menge 50 ul
Quantity options 100 ul 50 ul
Kategorie
Typ Antibody Polyclonal
Applikationen WB, IF, IHC
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Konjugat/Tag Unconjugated
Purity The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Histone deacetylase 5, Short name=HD5, Antigen NY-CO-9, HDAC-5, KIAA0600
Similar products HDAC5
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Application Notes
WB: 1:500~1:1000
IHC: 1:50~1:200
IF: 1:50~1:200
Background
HDAC5 is a member of the class II mammalian histone deacetylase family, which is structurally related to yeast HDA1. Human HDAC5 is composed of 1122 amino acid residues. The deacetylase domain of HDAC5 is located at the C-terminal half of the molecule. The N-terminal non-deacetylase domain does not show any significant homology with any published sequence.Both domains are required for HDAC5-mediated repression of gene transcription. HDAC5 interacts with a growing number of transcriptional factors including MEF2A as well as other HDAC proteins. The interacting complexes bind to specific regions of chromatin and regulate gene transcription in these regions.
Manufacturer - Product
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Manufacturer - Specificity
HDAC5 (E1106) polyclonal antibody detects endogenous levels of HDAC5 protein.
Molecular Weight
~ 121 kDa
Note
For research use only, not for use in diagnostic procedure.
Pathway
Notch Signaling, Nuclear Receptor Signaling, Cell Cycle Control G1 S Checkpoint, Epigenetic Writers and Erasers of Histone H3, Epigenetic Writers and Erasers of Histones H2A H2B and H4
Immunogen
Synthetic peptide, corresponding to the C-terminus of Human HDAC5.
Modification
Unmodification

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ul
Lieferbar: In stock
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