ArtNr |
BS1163-100 |
Hersteller |
Bioworld Technology, Inc
|
Menge |
100 ul |
Quantity options |
100 ul
50 ul
|
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB, IF, IHC |
Specific against |
Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus) |
Host |
Rabbit |
Konjugat/Tag |
Unconjugated |
Purity |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Histone deacetylase 5, Short name=HD5, Antigen NY-CO-9, HDAC-5, KIAA0600 |
Similar products |
HDAC5 |
Lieferbar |
|
Application Notes |
WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200 |
Background |
HDAC5 is a member of the class II mammalian histone deacetylase family, which is structurally related to yeast HDA1. Human HDAC5 is composed of 1122 amino acid residues. The deacetylase domain of HDAC5 is located at the C-terminal half of the molecule. The N-terminal non-deacetylase domain does not show any significant homology with any published sequence.Both domains are required for HDAC5-mediated repression of gene transcription. HDAC5 interacts with a growing number of transcriptional factors including MEF2A as well as other HDAC proteins. The interacting complexes bind to specific regions of chromatin and regulate gene transcription in these regions. |
Manufacturer - Product |
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 |
Manufacturer - Specificity |
HDAC5 (E1106) polyclonal antibody detects endogenous levels of HDAC5 protein. |
Molecular Weight |
~ 121 kDa |
Note |
For research use only, not for use in diagnostic procedure. |
Pathway |
Notch Signaling, Nuclear Receptor Signaling, Cell Cycle Control G1 S Checkpoint, Epigenetic Writers and Erasers of Histone H3, Epigenetic Writers and Erasers of Histones H2A H2B and H4 |
Immunogen |
Synthetic peptide, corresponding to the C-terminus of Human HDAC5. |
Modification |
Unmodification |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.