ArtNr |
BS1107-100 |
Hersteller |
Bioworld Technology, Inc
|
Menge |
100ul |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB, IHC |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
ELK 1, Elk1, ELK1 member of ETS oncogene family, ELK1 protein, ELK1, ELK2 member of ETS oncogene family, ETS domain containing protein Elk 1, ETS domain containing protein Elk1, ETS domain protein Elk1, ETS domain-containing protein Elk-1, ETS like gene 1 |
Similar products |
Elk1 |
Lieferbar |
|
Swiss-Prot |
P19419 |
Application all |
WB: 1:500ca.1:1000 IHC: 1:50ca.1:200 |
Background |
Ets-1 is the prototype member of a family of genes identified on the basis of homology to the v-Ets oncogene isolated from the E26 erythroblastosis virus. This family of genes currently includes Ets-1, Ets-2, Erg-1-3, Elk-1, Elf-1, Elf-5, NERF, PU.1, PEA3, ERM, FEV, ER8l, Fli-1, TEL, Spi-B, ESE-1, ESE-3A, Net, ABT1 and ERF. Members of the Ets gene family exhibit varied patterns of tissue expression, and share a highly conserved carboxy-terminal domain containing a sequence related to the SV40 large T antigen nuclear localization signal sequence. This conserved domain is essential for Ets-1 binding to DNA and is likely to be responsible for the DNA binding activity of all members of the Ets gene family. Several of these proteins have been shown to recognize similar motifs in DNA that share a centrally located 5'-GGAA-3' element. |
Product |
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. |
Purification and Purity |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). |
Storage and Stability |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Specificity |
Elk1 (S411) pAb detects endogenous levels of Elk1 protein. |
WB |
Western blot (WB) analysis of Elk1 (S411) pAb at 1:500 dilution Lane1:Hela cell lysate Lane2:sp2/0 cell lysate Lane3:H9C2 cell lysate |
IHC |
Immunohistochemistry (IHC) analyzes of Elk1 (S411) pAb in paraffin-embedded human breast carcinoma tissue at 1:100. |
BiowMW |
ca. 45 kDa |
Note |
For research use only, not for use in diagnostic procedure. |
Alternative Name |
ELK 1, Elk1, ELK1 member of ETS oncogene family, ELK1 protein, ELK1, ELK2 member of ETS oncogene family, ETS domain containing protein Elk 1, ETS domain containing protein Elk1, ETS domain protein Elk1, ETS domain-containing protein Elk-1, ETS like gene 1, Member of ETS oncogene family, Oncogene Elk1, Tyrosine kinase (ELK1) oncogene, |
Immunogen |
Synthetic peptide, corresponding to amino acids 380-430 of Human Elk1. |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.