ArtNr |
AP0686-100 |
Hersteller |
Bioworld Technology, Inc
|
Menge |
100 ul |
Quantity options |
100 ul
50 ul
|
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB |
Specific against |
Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus) |
Host |
Rabbit |
Konjugat/Tag |
Unconjugated |
Purity |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 116% (by SDS-PAGE). |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Peroxisome proliferator-activated receptor gamma, Short name=PPAR-gamma, Nuclear receptor subfamily 1 group C member 3, PPARG, NR1C3, PPAR γ, PPARγ |
Similar products |
PPAR-gamma |
Lieferbar |
|
Application Notes |
WB: 1:500~1:1000 |
Background |
PPAR gamma is implicated in numerous diseases including obesity, diabetes, atherosclerosis and cancer. PPAR gamma activators include prostanoids, fatty acids, thiazolidinediones and N-(2-benzoylphenyl) tyrosine analogues. A key component in adipocyte differentiation and fat-specific gene expression, PPAR gamma may modulate macrophage functions such as proinflammatory activities, and stimulate oxidized low-density lipoprotein (x-LDL) uptake. A Pro12Ala polymorphism of the PPAR gamma2 gene has been reported to reduce transactivation activity in vitro. This substitution may affect the immune response to ox-LDL and be associated with type 2 diabetes. In addition, the Pro12Ala variant of the PPAR gamma2 gene maybe correlated with abdominal obesity in type 2 diabetes. |
Manufacturer - Product |
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 |
Manufacturer - Specificity |
PPAR-γ (K160) polyclonal antibody detects endogenous levels of PPAR gamma protein. |
Molecular Weight |
~ 54 kDa |
Note |
For research use only, not for use in diagnostic procedure. |
Pathway |
Nuclear Receptor Signaling, MTOR signaling |
Immunogen |
Synthetic peptide, corresponding to amino acids 130-180 of Human PPAR-γ. |
Modification |
Unmodification |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.