ArtNr |
MB0120-50 |
Hersteller |
Bioworld Technology, Inc
|
Menge |
50ul |
Kategorie |
|
Typ |
Antibody Monoclonal |
Applikationen |
WB |
Specific against |
Human, Mouse |
Host |
Mouse |
Isotype |
IgG1 |
ECLASS 10.1 |
42030590 |
ECLASS 11.0 |
42030590 |
UNSPSC |
12352203 |
Alias |
Crocalbin, IEF SSP 9302, CALU |
Similar products |
Calumenin |
Lieferbar |
|
Swiss-Prot |
O43852 |
Application all |
WB:1:1000 |
Background |
Caluminin is a 315 amino acid Ca2+-binding member of the CREC, EF-hand protein family. Calumenin is a secreted protein t hat contains six Ca2+-binding (EF-hand) motifs and is expressed in the lumen of the endoplasmic reticulum (ER) and Golgi apparatus. In the presence of Ca2+, Calumenin interacts with serum amyloid P component (SAP) and, together, they may play a role in the immunological defense system and participate in amyloidosis, the pathological formation of amyloid deposits in different types of tissues. Calumenin has an inhibitory effect on the vitamin K-dependent g-carboxylation system which converts vitamin K-dependent proteins to Gla-containing proteins. Calumenin may also be involved in the pathophysiology of thrombosis and/or wound healing by acting in an autocrine or paracrine manner. |
Product |
Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol |
Purification and Purity |
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). |
Storage and Stability |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Specificity |
Calumenin (C-terminus) mAb detects endogenous levels of Calumenin protein. |
WB |
Western blot detection of CALU in SW480, mouse intestine &A431 cell lysates and using CALU antibody (1:1000 diluted) . |
BiowMW |
Predicted band size:37KDa Observed band size:45KDa |
Note |
For research use only, not for use in diagnostic procedure. |
Alternative Name |
Crocalbin, IEF SSP 9302, CALU |
Immunogen |
Synthetic peptide, corresponding to amino acids C-terminus of Human Calumenin. |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.