ArtNr |
BS9947M-50 |
Hersteller |
Bioworld Technology, Inc
|
Menge |
50ul |
Kategorie |
|
Typ |
Antibody Monoclonal |
Applikationen |
WB, FC, IHC |
Specific against |
Human, Mouse |
Host |
Rabbit |
ECLASS 5.1 |
32160702 |
ECLASS 6.1 |
32160702 |
ECLASS 8.0 |
32160702 |
ECLASS 9.0 |
42030590 |
ECLASS 10.0.1 |
42030590 |
ECLASS 10.1 |
42030590 |
ECLASS 11.0 |
42030590 |
UNSPSC |
12352203 |
Alias |
Keratin, type I cytoskeletal 15, Cytokeratin-15, Short name=CK-15, Keratin-15, Short name=K15, KRT15, KRTB, Keratin 15, CK15, CK 15, Keratin15 |
Lieferbar |
|
Buffer composition |
Recombinant Rabbit Monoclonal Antibody. 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
Background |
Cytokeratin 15 is an intermediate filament (IF) type I protein that is responsible for the mechanical integrity of epithelial cells. Keratin family members are subdivided into cytokeratins and hair keratins. Cytokeratin 15 is a specific marker of stem cells of the hair-follicle bulge and may be a useful marker for diagnosis between basal cell carcinoma and trichoepithelioma. Trichoblastoma are benign neoplasms of follicular differentiation frequently found in nevus sebaceus. Many morphologic features are shared with nodular basal cell carcinoma, sometimes rendering a diagnosis difficult. Trichoblastoma and BCC show variable expression of Cytokeratin 15 and Cytokeratin 19, and absence of hair keratins. |
Application info |
WB: 1:1, 000-1:2, 000 IHC/IF: 1:50-1:200 FC: 1:50-1:100 |
Swiss-Prot |
P19012 |
Purification and Purity |
Protein A affinity purified |
Storage and Stability |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Specificity |
This antibody detects endogenous levels of Cytokeratin 15 and does not cross-react with related proteins. |
BiowMW |
ca. 49 kDa |
Note |
For research use only, not for use in diagnostic procedure. |
Alternative Name |
Keratin, type I cytoskeletal 15, Cytokeratin-15, Short name=CK-15, Keratin-15, Short name=K15, KRT15, KRTB, Keratin 15, CK15, CK 15, Keratin15 |
Immunogen |
Recombinant antibody. |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.