ArtNr |
BS9947M-100 |
Hersteller |
Bioworld Technology, Inc
|
Menge |
100 ul |
Quantity options |
100 ul
50 ul
|
Kategorie |
|
Typ |
Antibody Monoclonal |
Applikationen |
WB, FC, IHC |
Specific against |
Human (Homo sapiens), Mouse (Murine, Mus musculus) |
Host |
Rabbit |
Konjugat/Tag |
Unconjugated |
Purity |
Protein A affinity purified |
ECLASS 10.1 |
42030590 |
ECLASS 11.0 |
42030590 |
UNSPSC |
12352203 |
Alias |
Keratin, type I cytoskeletal 15, Cytokeratin-15, Short name=CK-15, Keratin-15, Short name=K15, KRT15, KRTB, Keratin 15, CK15, CK 15, Keratin15 |
Lieferbar |
|
Application Notes |
WB: 1:1000-1:2000 IHC/IF: 1:50-1:200 FC: 1:50-1:100 |
Background |
Cytokeratin 15 is an intermediate filament (IF) type I protein that is responsible for the mechanical integrity of epithelial cells. Keratin family members are subdivided into cytokeratins and hair keratins. Cytokeratin 15 is a specific marker of stem cells of the hair-follicle bulge and may be a useful marker for diagnosis between basal cell carcinoma and trichoepithelioma. Trichoblastoma are benign neoplasms of follicular differentiation frequently found in nevus sebaceus. Many morphologic features are shared with nodular basal cell carcinoma, sometimes rendering a diagnosis difficult. Trichoblastoma and BCC show variable expression of Cytokeratin 15 and Cytokeratin 19, and absence of hair keratins. |
Manufacturer - Product |
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 |
Manufacturer - Specificity |
This antibody detects endogenous levels of Cytokeratin 15 and does not cross-react with related proteins. |
Molecular Weight |
~ 49 kDa |
Note |
For research use only, not for use in diagnostic procedure. |
Immunogen |
Recombinant antibody. |
Modification |
Unmodification |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.