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HSD17B2 polyclonal antibody

HSD17B2 polyclonal antibody

ArtNr	BS7340-50
Hersteller	Bioworld Technology, Inc
Menge	50ul
Kategorie	Food Safety Hormones Metabolism Diabetes Antibodies Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB, IF, IHC
Specific against	Human, Mouse
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	17 beta HSD 2, 17-beta-HSD 2, 17-beta-hydroxysteroid dehydrogenase type 2, 20 alpha HSD, 20 alpha hydroxysteroid dehydrogenase, 20 alpha-hydroxysteroid dehydrogenase, 20-alpha-HSD, DHB2_HUMAN, E2DH, EDH17B2, Estradiol 17-beta-dehydrogenase 2, HSD17, Hsd17
Similar products	HSD17B2
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Swiss-Prot	P37059
Application all	WB: 1:500ca.1:2000 IHC/IF: 1:50ca.1:200
Background	17beta-HSD2 (17beta hydroxysteroid dehydrogenase type 2) belongs to the 17beta-HSD family of proteins that regulate the availability of steroids within a tissue. 17beta-HSD2 converts active steroids to their inactive form through its oxidative activity. It is a key player in the inactivation of Estradiol and testosterone. Due to the affects that 17beta-HSD2 has on the availability of estrogen, it has been extensively investigated for playing a possible role in breast tumor development, colon cancer development and the pathophysiology of endometriosis.
Product	1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Purification and Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Specificity	HSD17B2 pAb detects endogenous levels of HSD17B2 protein.
WB	Western blot (WB) analysis of HSD17B2 polyclonal antibody
IHC	Immunohistochemistry (IHC) analysis of HSD17B2 polyclonal antibody in paraffin-embedded Rat Brain tissue.
IF	Immunofluorescence analysis of U2OS cells, using HSD17B2 polyclonal antibody
BiowMW	ca. 42 kDa
Note	For research use only, not for use in diagnostic procedure.
Alternative Name	17 beta HSD 2, 17-beta-HSD 2, 17-beta-hydroxysteroid dehydrogenase type 2, 20 alpha HSD, 20 alpha hydroxysteroid dehydrogenase, 20 alpha-hydroxysteroid dehydrogenase, 20-alpha-HSD, DHB2_HUMAN, E2DH, EDH17B2, Estradiol 17-beta-dehydrogenase 2, HSD17, Hsd17b2, Hydroxysteroid (17 beta) dehydrogenase 2, Microsomal 17 beta hydroxysteroid dehydrogenase, Microsomal 17-beta-hydroxysteroid dehydrogenase, SDR9C2, Testosterone 17 beta dehydrogenase, Testosterone 17-beta-dehydrogenase
Immunogen	Recombinant full length Human HSD17B2.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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