ArtNr |
BS7340-50 |
Hersteller |
Bioworld Technology, Inc
|
Menge |
50ul |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB, IF, IHC |
Specific against |
Human, Mouse |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
17 beta HSD 2, 17-beta-HSD 2, 17-beta-hydroxysteroid dehydrogenase type 2, 20 alpha HSD, 20 alpha hydroxysteroid dehydrogenase, 20 alpha-hydroxysteroid dehydrogenase, 20-alpha-HSD, DHB2_HUMAN, E2DH, EDH17B2, Estradiol 17-beta-dehydrogenase 2, HSD17, Hsd17 |
Similar products |
HSD17B2 |
Lieferbar |
|
Swiss-Prot |
P37059 |
Application all |
WB: 1:500ca.1:2000 IHC/IF: 1:50ca.1:200 |
Background |
17beta-HSD2 (17beta hydroxysteroid dehydrogenase type 2) belongs to the 17beta-HSD family of proteins that regulate the availability of steroids within a tissue. 17beta-HSD2 converts active steroids to their inactive form through its oxidative activity. It is a key player in the inactivation of Estradiol and testosterone. Due to the affects that 17beta-HSD2 has on the availability of estrogen, it has been extensively investigated for playing a possible role in breast tumor development, colon cancer development and the pathophysiology of endometriosis. |
Product |
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. |
Purification and Purity |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). |
Storage and Stability |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Specificity |
HSD17B2 pAb detects endogenous levels of HSD17B2 protein. |
WB |
Western blot (WB) analysis of HSD17B2 polyclonal antibody |
IHC |
Immunohistochemistry (IHC) analysis of HSD17B2 polyclonal antibody in paraffin-embedded Rat Brain tissue. |
IF |
Immunofluorescence analysis of U2OS cells, using HSD17B2 polyclonal antibody |
BiowMW |
ca. 42 kDa |
Note |
For research use only, not for use in diagnostic procedure. |
Alternative Name |
17 beta HSD 2, 17-beta-HSD 2, 17-beta-hydroxysteroid dehydrogenase type 2, 20 alpha HSD, 20 alpha hydroxysteroid dehydrogenase, 20 alpha-hydroxysteroid dehydrogenase, 20-alpha-HSD, DHB2_HUMAN, E2DH, EDH17B2, Estradiol 17-beta-dehydrogenase 2, HSD17, Hsd17b2, Hydroxysteroid (17 beta) dehydrogenase 2, Microsomal 17 beta hydroxysteroid dehydrogenase, Microsomal 17-beta-hydroxysteroid dehydrogenase, SDR9C2, Testosterone 17 beta dehydrogenase, Testosterone 17-beta-dehydrogenase |
Immunogen |
Recombinant full length Human HSD17B2. |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.