ArtNr |
BS2908-50 |
Hersteller |
Bioworld Technology, Inc
|
Menge |
50ul |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB, IHC |
Specific against |
Human, Mouse |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Transcription factor GATA-5, GATA-binding factor 5, GATA5 |
Similar products |
GATA-5 |
Lieferbar |
|
Swiss-Prot |
Q9BWX5 |
Application all |
WB: 1:500ca.1:1000
IHC: 1:50ca.1:200 |
Background |
The protein encoded by this gene is a transcription factor that contains two GATA type zinc fingers. The encoded protein is known to bind to hepatocyte nuclear factor-1alpha (HNF 1 alpha), and this interaction is essential for cooperative activation of the intestinal lactase phlorizin hydrolase promoter. In other organisms, similar proteins may be involved in the establishment of cardiac smooth muscle cell diversity. GATA5 is induced at an early stage of endothelial-endocardial differentiation prior to expression of such early endocardial markers as Tie2 and ErbB3. It is required for differentiation of cardiogenic precursors into endothelial endocardial cells. |
Product |
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. |
Purification and Purity |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). |
Storage and Stability |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Specificity |
GATA-5 (K293) pAb detects endogenous levels of GATA-5 protein. |
IHC |
Immunohistochemistry (IHC) analyzes of GATA-5 (K293) pAb in paraffin-embedded human breast carcinoma tissue at 1:100. |
BiowMW |
ca. 41 kDa |
Note |
For research use only, not for use in diagnostic procedure. |
Alternative Name |
Transcription factor GATA-5, GATA-binding factor 5, GATA5 |
Immunogen |
Synthetic peptide, corresponding to amino acids 260-313 of Human GATA-5. |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.