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RPA2 (A17) polyclonal antibody

RPA2 (A17) polyclonal antibody

ArtNr	BS1692-50
Hersteller	Bioworld Technology, Inc
Menge	50ul
Kategorie	Neuroscience Neural Lineage Markers Neural Transcription Factors Antibodies Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB, IF, IHC
Specific against	Human, Mouse
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Replication protein A 32 kDa subunit, RP-A p32, RF-A protein 2, RPA2, REPA2, RPA32, RPA34
Similar products	RPA2
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Swiss-Prot	P15927
Application all	WB: 1:500ca.1:1000 IHC: 1:50ca.1:200 IF: 1:50ca.1:200
Background	RPA is a major damage-recognition protein involved in the early stages of nucleotide excision repair. It can also play a role in telomere maintenance. The C-terminus of RPA 32 can specfically intereact with the DNA repair enzyme UNG2 and repair factors XPA and Rad52, each of which functions in a different repair pathway. In addition, RPA 32 binds specifically to the SH2 domain of Stat3 in vivo, and overexpression of RPA 32 corresponds to the augmented growth factor-stimulated tyrosine phosphorylation and transcription activities of Stat3.
Product	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Purification and Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Specificity	RPA2 (A17) pAb detects endogenous levels of RPA2 protein.
IHC	Immunohistochemistry (IHC) analyzes of RPA2 (A17) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.
BiowMW	ca. 32 kDa
Note	For research use only, not for use in diagnostic procedure.
Alternative Name	Replication protein A 32 kDa subunit, RP-A p32, RF-A protein 2, RPA2, REPA2, RPA32, RPA34
Immunogen	Synthetic peptide, corresponding to the N-terminus of Human RPA2.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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