Hersteller |
Bioworld Technology, Inc
|
Kategorie |
|
Typ |
Antibody Polyclonal |
Specific against |
Human |
Applikationen |
WB, IF, IHC |
Menge |
100ul |
Host |
Rabbit |
ArtNr |
BS70774-100 |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Lieferbar |
|
Alias |
KKLF, Krueppel-like factor 15 |
Buffer composition |
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Background |
KLF15, KLF6 and KLF3 are Krüppel-like zinc finger-containing transcription factors. KLF15, a kidney-enriched Krüppel-like factor, is a transcriptonal activator that binds the CLCNKA promoter. KLF6 (also designated Zf9 or CPBP, for core promoter-binding protein) is rapidly induced during hepatic stellate cell activation and transactivates a reporter gene driven by the Collagen I promoter, suggesting that KLF6 plays a role in the response to tissue injury. KLF3 may play a role in hematopoiesis. KLF15, which is a nuclear protein, is expressed primarily in liver, heart, skeletal muscle and kidney tissues but is not detected in lymphoid tissues or bone marrow. It is an important regulator of GLUT4 in both adipose and muscle tissues. |
Application info |
WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100 |
Swiss-Prot |
Q9UIH9 |
Purification and Purity |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). |
Storage and Stability |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Specificity |
KLF15 polyclonal antibody detects endogenous levels of KLF15 protein. |
BiowMW |
ca. 44 kDa |
Note |
For research use only, not for use in diagnostic procedure. |
Alternative Name |
KKLF, Krueppel-like factor 15 |
Immunogen |
Recombinant protein of human KLF15. |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.