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m-anti-TNF (IgG), monoclonal

m-anti-TNF (IgG), monoclonal

ArtNr	BTZ-12500001
Hersteller	BioTeZ
Menge	0.1 mg
Kategorie	Antibodies ELISA Primary Antibodies
Typ	Antibody Monoclonal
Format	Lyophilized
Applikationen	ELISA
Specific against	Human
Host	Mouse
Isotype	IgG2a
ECLASS 5.1	32160702
ECLASS 6.1	32160702
ECLASS 8.0	32160702
ECLASS 9.0	42030590
ECLASS 10.0.1	42030590
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
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Description	Mab to human TNF. Immunoglobulin isotype: IgG2a. The monoclonal antibody was raised against recombinant human tumor necrose factor alpha (TNFa). The immune lymphocytes from BALB/c mice were extracted from lymph nodes and fused with myeloma sp2/0 cells according to a standard protocol. The IgG1 fraction was purified by Protein G affinity chromatography. The antibody has been reported for use in detection of human TNF alpha by ELISA. It can also be used for immunoblotting.
Pathway and Disease	Autoimmune disease
Applications Info	ELISA Immunoblotting
Product Citations	1. Strohner P: Patent: EP 1957980B1 Immunoassay for the simultaneous immunochemical determination of an analyte (antigen) and a treatment antibody targeting the analyte in samples (Recovery immunoassay) 2. Korn S, Haasler I, Jung M, Strohner P, Staatz A, Schäfer A, Becher G, Taube C and Buhl R Free serum IgE in patients with severe allergic asthma treated with Omalizumab Am. J. Respir. Crit. Care Med., May 2010; 181: A6655 3. Strohner P, Sarrach D, Reich JG, Becher G, Staatz A, Schäfer A, Steiß J-O, Häupl T: The Recovery-ELISA – a novel Assay Technique for the Therapy Control of Therapeutic Antibodies Am J Respir Crit Care Med 181; 2010:A5674 4. Strohner P, Staatz A, Schäfer A, Becher G, Sarrach D, Reich JG, Steiß J-O, Häupl T: Monitoring of Monoclonal Antibody Therapy with a new Recovery ELISA Assay Technique (R-ELISA) ERS Barcelona 2010, Abstract-No: 3399 5. Steiß JO, Schmidt A, Lindemann H, Rudloff S, Staatz A, Strohner P, Becher G, Nährlich L, Zimmer KP: Therapiemonitoring von Omalizumab im Kindes- und Jugendalter. Allergologie, Jahrgang 33, Nr. 10/2010, S. 421–428
Alternate Names	Mab to human TNF. Immunoglobulin isotype: IgG2a. The monoclonal antibody was raised against recombinant human tumor necrose factor alpha (TNFa). The immune lymphocytes from BALB/c mice were extracted from lymph nodes and fused with myeloma sp2/0 cells according to a standard protocol. The IgG1 fraction was purified by Protein G affinity chromatography. The antibody has been reported for use in detection of human TNF alpha by ELISA. It can also be used for immunoblotting.
Accession No	P01376
Composition	PBS, with 0, 1% Azide
Purity	>95% pure. Purity is tested by electrophoresis.
Antigen	recombinant human TNF
Storage	-20C long term; +4C short term
Conjugate	with label on request, e.g. Biotin, HRP
Cross Reactivity	no crossreactivty
No Cross Reactivity	no crossreactivty to human Cold inducible Binding protein (CIRBP)
Specificity	recombinant and human TNF
Purification	Protein G purified
Shipping Temp (Min)	-80C +37C
Restrictions	For Research Use only.

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Menge: 0.1 mg

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Lieferung vsl. bis 02.08.2024

Express-Lieferung: 9 Tage sparen

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