ArtNr |
BM-RPC26121-1mg |
Hersteller |
Biomatik
|
Menge |
1mg |
Kategorie |
|
Typ |
Proteins Recombinant |
Specific against |
other |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Lieferbar |
|
Gene Name |
CHRNA1 |
Uniprot |
P02710 |
Source |
Yeast |
Expression Region |
25-234aa |
AA Sequence |
SEHETRLVANLLENYNKVIRPVEHHTHFVDITVGL QLIQLISVDEVNQIVETNVRLRQQWIDVRLRWNPA DYGGIKKIRLPSDDVWLPDLVLYNNADGDFAIVHM TKLLLDYTGKIMWTPPAIFKSYCEIIVTHFPFDQQ NCTMKLGIWTYDGTKVSISPESDRPDLSTFMESGE WVMKDYRGWKHWVYYTCCPDTPYLDITYHFIMQRI |
Sequence Info |
Partial |
Tag Info |
N-terminal 6xHis-sumostar-tagged |
Theoretical MW |
37.9 kDa |
Purity |
>85% as determined by SDS-PAGE. |
Storage Buffer |
Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. |
Endotoxin Level |
Not tested |
Biological Activity |
Not tested |
Shipping Condition |
Ice packs |
Storage |
Short term: -20CC; Long term: -80CC. Minimize freeze and thaw cycles. |
Expiry Date |
1 year |
Restriction |
For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals. |
Relevance |
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. |
Function |
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. |
Subcellular location |
Cell junction, synapse, postsynaptic cell membrane, Multi-pass membrane protein, Cell membrane, Multi-pass membrane protein |
Protein Families |
Ligand-gated ion channel (TC 1.A.9) family, Acetylcholine receptor (TC 1.A.9.1) subfamily, Alpha-1/CHRNA1 sub-subfamily |
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