ArtNr |
BM-RPC26760-100ug |
Hersteller |
Biomatik
|
Menge |
100ug |
Kategorie |
|
Typ |
Proteins Recombinant |
Specific against |
Human |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
DHH, |
Similar products |
DHH |
Lieferbar |
|
Gene Name |
DHH |
Alternative Names |
DHH, |
Uniprot |
O43323 |
Source |
E.coli |
Expression Region |
24-198aa |
AA Sequence |
II+GPGRGPVG RRRYARKQLV PLLYKQFVPG V PERTLGASG PAEGRVARGS ERFRDLVPNY NPD IIFKDEE NSGADRLMTE RCKERVNALA IAVMN MWPGV RLRVTEGWDE DGHHAQDSLH YEGRALD ITT SDRDRNKYGL LARLAVEAGF DWVYYESRN H VHVSVKADNS LAVRAGG |
Sequence Info |
Partial |
Tag Info |
Tag-Free |
Theoretical MW |
19.9 kDa |
Purity |
>96% as determined by SDS-PAGE and HPLC. |
Storage Buffer |
Lyophilized from a 0.2 um filtered 10mM PB, pH 6.0, 300mM NaCl |
Endotoxin Level |
Less than 1.0 EU/ug as determined by LAL method. |
Biological Activity |
The ED50 as determined by its ability to induce alkaline phosphatase production by C3H10T1/2(CCL-226) cells is 15-45 ug/ml. |
Shipping Condition |
Ice packs |
Storage |
Short term: -20CC; Long term: -80CC. Minimize freeze and thaw cycles. |
Expiry Date |
1 year |
Restriction |
For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals. |
Relevance |
Intercellular signal essential for a variety of patterning events during development. May function as a spermatocyte survival factor in the testes. Essential for testes development. |
Function |
Intercellular signal essential for a variety of patterning events during development. May function as a spermatocyte survival factor in the testes. Essential for testes development. |
Involvement in disease |
Partial gonadal dysgenesis with minifascicular neuropathy 46, XY (PGD); 46, XY sex reversal 7 (SRXY7) |
Subcellular location |
Desert hedgehog protein N-product: Cell membrane, Lipid-anchor, Extracellular side, Note=The N-terminal peptide remains associated with the cell surface, SUBCELLULAR LOCATION: Desert hedgehog protein C-product: Secreted, extracellular space |
Protein Families |
Hedgehog family |
Paythway |
Hedgehogsignalingpathway |
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