ArtNr |
BM-RPC26035-50ug |
Hersteller |
Biomatik
|
Menge |
50ug |
Kategorie |
|
Typ |
Proteins Recombinant |
Specific against |
Bovine |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
Adrenal ferredoxin (Ferredoxin-1) (Hepato-ferredoxin) (ADX) |
Similar products |
Adrenal ferredoxin (Ferredoxin-1) (Hepato-ferredoxin) (ADX) |
Lieferbar |
|
Gene Name |
FDX1 |
Alternative Names |
Adrenal ferredoxin (Ferredoxin-1) (Hepato-ferredoxin) (ADX) |
Uniprot |
P00257 |
Source |
Yeast |
Expression Region |
59-186aa |
AA Sequence |
SSSEDKITVHFINRDGETLTTKGKIGDSLLDVVVQ NNLDIDGFGACEGTLACSTCHLIFEQHIFEKLEAI TDEENDMLDLAYGLTDRSRLGCQICLTKAMDNMTV RVPDAVSDARESIDMGMNSSKIE |
Sequence Info |
Full Length of Mature Protein |
Tag Info |
N-terminal 6xHis-tagged |
Theoretical MW |
15.3 kDa |
Purity |
>85% as determined by SDS-PAGE. |
Storage Buffer |
Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. |
Endotoxin Level |
Not tested |
Biological Activity |
Not tested |
Shipping Condition |
Ice packs |
Storage |
Short term: -20CC; Long term: -80CC. Minimize freeze and thaw cycles. |
Expiry Date |
1 year |
Restriction |
For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals. |
Relevance |
Essential for the synthesis of various steroid hormones. Participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis. Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage to produce pregnenolone, the precursor of most steroid hormones. Does not form a ternary complex with adrenodoxin reductase and CYP11A1 but shuttles between the two enzymes to transfer electrons. |
Function |
Essential for the synthesis of various steroid hormones, participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis. Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage (By similarity). |
Subcellular location |
Mitochondrion matrix |
Protein Families |
Adrenodoxin/putidaredoxin family |
Tissue Specificity |
Detected in adrenal cortex and corpus luteum (at protein level). |
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