CLC-4 Polyclonal Antibody

Polyclonal

Synthesized peptide derived from the Internal region of human CLC-4. at AA rangle: 190-270

CLCN4; H (+)/Cl (-) exchange transporter 4; Chloride channel protein 4; ClC-4; Chloride transporter ClC-4

P51793

1 mg/ml

1 year

The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. Chloride channel 4 has an evolutionary conserved CpG island and is conserved in both mouse and hamster. CLCN4 is mapped in close proximity to APXL (Apical protein Xenopus laevis-like) and OA1 (Ocular albinism type I), which are both located on the human X chromosome at band p22.3. The physiological role of chloride channel 4 remains unknown but may contribute to the pathogenesis of neuronal disorders. Alternate splicing results in two transcript variants that encode different proteins.