ArtNr |
BM-CAC07329-50ug |
Hersteller |
Biomatik
|
Menge |
50ug |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
WB, IHC, ELISA |
Specific against |
Human, Mouse |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
TEA domain family member 4,Transcription factor 13-like 1,Transcription factor RTEF-1,RTEF1, TCF13L1, TEF3,TEAD4 |
Lieferbar |
|
Immunogen |
Recombinant human Transcriptional enhancer factor TEF-3 protein (74-434AA) |
Conjugate |
Unconjugated |
Alternative Names |
TEA domain family member 4, Transcription factor 13-like 1, Transcription factor RTEF-1, RTEF1, TCF13L1, TEF3, TEAD4 |
UniProt ID |
Q15561 |
Purification |
Caprylic Acid Ammonium Sulfate Precipitation Purified |
Storage Instructions |
Aliquot and store at -20C. Minimize freezing and thawing. |
Expiry Date |
1 year |
Shipping Condition |
Blue ice |
Comment |
Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds specifically and non-cooperatively to the Sph and GT-IIC 'enhansons' (5'-GTGGAATGT-3') and activates transcription. Binds to the M-CAT motif. |
Restriction |
For research use only. Not for diagnostic procedures. |
Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.
Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.